Home >> Research Area >>Natural Products>>Xanthones>> Rheediaxanthone A

Rheediaxanthone A

CAS# 77181-97-6

Rheediaxanthone A

Catalog No. BCN7411----Order now to get a substantial discount!

Product Name & Size Price Stock
Rheediaxanthone A: 5mg Please Inquire In Stock
Rheediaxanthone A: 10mg Please Inquire In Stock
Rheediaxanthone A: 20mg Please Inquire Please Inquire
Rheediaxanthone A: 50mg Please Inquire Please Inquire
Rheediaxanthone A: 100mg Please Inquire Please Inquire
Rheediaxanthone A: 200mg Please Inquire Please Inquire
Rheediaxanthone A: 500mg Please Inquire Please Inquire
Rheediaxanthone A: 1000mg Please Inquire Please Inquire

Quality Control of Rheediaxanthone A

Number of papers citing our products

Chemical structure

Rheediaxanthone A

3D structure

Chemical Properties of Rheediaxanthone A

Cas No. 77181-97-6 SDF Download SDF
PubChem ID 102060338 Appearance Powder
Formula C23H20O6 M.Wt 392.40
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 11,22-dihydroxy-7,7,19,19-tetramethyl-2,8,20-trioxapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(14),3(12),4(9),5,10,15,17,21-octaen-13-one
SMILES CC1(C=CC2=C(O1)C(=C3C(=C2)C(=O)C4=C(C=C5C(=C4O3)C=CC(O5)(C)C)O)O)C
Standard InChIKey GSAPUFLPLOSGII-UHFFFAOYSA-N
Standard InChI InChI=1S/C23H20O6/c1-22(2)8-6-12-15(28-22)10-14(24)16-17(25)13-9-11-5-7-23(3,4)29-19(11)18(26)21(13)27-20(12)16/h5-10,24,26H,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rheediaxanthone A

The stem bark of Calophyllum inophyllum.

Biological Activity of Rheediaxanthone A

DescriptionRheediaxanthone A is a natural product from Calophyllum inophyllum.
In vitro

Antiproliferative xanthone derivatives from Calophyllum inophyllum and Calophyllum soulattri.[Pubmed: 25730799]

Pak J Pharm Sci. 2015 Mar;28(2):425-9.


METHODS AND RESULTS:
Structure-activity relationships of eleven xanthones were comparatively predicted for four cancer cell lines after the compounds were subjected to antiproliferative assay against B-lymphocyte cells (Raji), colon carcinoma cells (LS174T), human neuroblastoma cells (IMR-32) and skin carcinoma cells (SK-MEL-28). The eleven chemical constituents were obtained naturally from the stem bark of Calophyllum inophyllum and Calophyllum soulattri. Inophinnin (1) and inophinone (2) were isolated from Calophyllum inophyllum while soulattrin (3) and phylattrin (4) were found from Calophyllum soulattri. The other xanthones were from both Calophyllum sp. and they are pyranojacareubin (5), Rheediaxanthone A (6), macluraxanthone (7), 4-hydroxyxanthone (8), caloxanthone C (9), brasixanthone B (10) and trapezifolixanthone (11).
CONCLUSIONS:
Compound 3 was found to be the most cytotoxic towards all the cancer cell lines with an IC50 value of 1.25μg/mL while the simplest xanthone, compound 8 was inactive.

Rheediaxanthone A Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Rheediaxanthone A Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Rheediaxanthone A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5484 mL 12.7421 mL 25.4842 mL 50.9684 mL 63.7105 mL
5 mM 0.5097 mL 2.5484 mL 5.0968 mL 10.1937 mL 12.7421 mL
10 mM 0.2548 mL 1.2742 mL 2.5484 mL 5.0968 mL 6.371 mL
50 mM 0.051 mL 0.2548 mL 0.5097 mL 1.0194 mL 1.2742 mL
100 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.5097 mL 0.6371 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Rheediaxanthone A

Antiproliferative xanthone derivatives from Calophyllum inophyllum and Calophyllum soulattri.[Pubmed:25730799]

Pak J Pharm Sci. 2015 Mar;28(2):425-9.

Structure-activity relationships of eleven xanthones were comparatively predicted for four cancer cell lines after the compounds were subjected to antiproliferative assay against B-lymphocyte cells (Raji), colon carcinoma cells (LS174T), human neuroblastoma cells (IMR-32) and skin carcinoma cells (SK-MEL-28). The eleven chemical constituents were obtained naturally from the stem bark of Calophyllum inophyllum and Calophyllum soulattri. Inophinnin (1) and inophinone (2) were isolated from Calophyllum inophyllum while soulattrin (3) and phylattrin (4) were found from Calophyllum soulattri. The other xanthones were from both Calophyllum sp. and they are pyranojacareubin (5), Rheediaxanthone A (6), macluraxanthone (7), 4-hydroxyxanthone (8), caloxanthone C (9), brasixanthone B (10) and trapezifolixanthone (11). Compound 3 was found to be the most cytotoxic towards all the cancer cell lines with an IC50 value of 1.25mug/mL while the simplest xanthone, compound 8 was inactive.

Keywords:

Rheediaxanthone A,77181-97-6,Natural Products, buy Rheediaxanthone A , Rheediaxanthone A supplier , purchase Rheediaxanthone A , Rheediaxanthone A cost , Rheediaxanthone A manufacturer , order Rheediaxanthone A , high purity Rheediaxanthone A

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: