Rheediaxanthone ACAS# 77181-97-6 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 77181-97-6 | SDF | Download SDF |
| PubChem ID | 102060338 | Appearance | Powder |
| Formula | C23H20O6 | M.Wt | 392.40 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 11,22-dihydroxy-7,7,19,19-tetramethyl-2,8,20-trioxapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(14),3(12),4(9),5,10,15,17,21-octaen-13-one | ||
| SMILES | CC1(C=CC2=C(O1)C(=C3C(=C2)C(=O)C4=C(C=C5C(=C4O3)C=CC(O5)(C)C)O)O)C | ||
| Standard InChIKey | GSAPUFLPLOSGII-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C23H20O6/c1-22(2)8-6-12-15(28-22)10-14(24)16-17(25)13-9-11-5-7-23(3,4)29-19(11)18(26)21(13)27-20(12)16/h5-10,24,26H,1-4H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Rheediaxanthone A is a natural product from Calophyllum inophyllum. |
| In vitro | Antiproliferative xanthone derivatives from Calophyllum inophyllum and Calophyllum soulattri.[Pubmed: 25730799]Pak J Pharm Sci. 2015 Mar;28(2):425-9.
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Rheediaxanthone A Dilution Calculator
Rheediaxanthone A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.5484 mL | 12.7421 mL | 25.4842 mL | 50.9684 mL | 63.7105 mL |
| 5 mM | 0.5097 mL | 2.5484 mL | 5.0968 mL | 10.1937 mL | 12.7421 mL |
| 10 mM | 0.2548 mL | 1.2742 mL | 2.5484 mL | 5.0968 mL | 6.371 mL |
| 50 mM | 0.051 mL | 0.2548 mL | 0.5097 mL | 1.0194 mL | 1.2742 mL |
| 100 mM | 0.0255 mL | 0.1274 mL | 0.2548 mL | 0.5097 mL | 0.6371 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antiproliferative xanthone derivatives from Calophyllum inophyllum and Calophyllum soulattri.[Pubmed:25730799]
Pak J Pharm Sci. 2015 Mar;28(2):425-9.
Structure-activity relationships of eleven xanthones were comparatively predicted for four cancer cell lines after the compounds were subjected to antiproliferative assay against B-lymphocyte cells (Raji), colon carcinoma cells (LS174T), human neuroblastoma cells (IMR-32) and skin carcinoma cells (SK-MEL-28). The eleven chemical constituents were obtained naturally from the stem bark of Calophyllum inophyllum and Calophyllum soulattri. Inophinnin (1) and inophinone (2) were isolated from Calophyllum inophyllum while soulattrin (3) and phylattrin (4) were found from Calophyllum soulattri. The other xanthones were from both Calophyllum sp. and they are pyranojacareubin (5), Rheediaxanthone A (6), macluraxanthone (7), 4-hydroxyxanthone (8), caloxanthone C (9), brasixanthone B (10) and trapezifolixanthone (11). Compound 3 was found to be the most cytotoxic towards all the cancer cell lines with an IC50 value of 1.25mug/mL while the simplest xanthone, compound 8 was inactive.
