Hyuganin DCAS# 77331-76-1 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 77331-76-1 | SDF | Download SDF |
| PubChem ID | 10317265 | Appearance | Powder |
| Formula | C20H22O7 | M.Wt | 374.38 |
| Type of Compound | Coumarins | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(9R,10R)-9-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-10-yl] 2-methylpropanoate | ||
| SMILES | CC(C)C(=O)OC1C(C(OC2=C1C3=C(C=C2)C=CC(=O)O3)(C)C)OC(=O)C | ||
| Standard InChIKey | BUTUNJHEBGRWGK-QZTJIDSGSA-N | ||
| Standard InChI | InChI=1S/C20H22O7/c1-10(2)19(23)26-17-15-13(27-20(4,5)18(17)24-11(3)21)8-6-12-7-9-14(22)25-16(12)15/h6-10,17-18H,1-5H3/t17-,18-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Hyuganin D can inhibit LPS-induced NO and/or TNF-alpha production in mouse peritoneal macrophages. |
| Targets | TNF-α | NO |
Hyuganin D Dilution Calculator
Hyuganin D Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6711 mL | 13.3554 mL | 26.7108 mL | 53.4217 mL | 66.7771 mL |
| 5 mM | 0.5342 mL | 2.6711 mL | 5.3422 mL | 10.6843 mL | 13.3554 mL |
| 10 mM | 0.2671 mL | 1.3355 mL | 2.6711 mL | 5.3422 mL | 6.6777 mL |
| 50 mM | 0.0534 mL | 0.2671 mL | 0.5342 mL | 1.0684 mL | 1.3355 mL |
| 100 mM | 0.0267 mL | 0.1336 mL | 0.2671 mL | 0.5342 mL | 0.6678 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- SL 0101-1
Catalog No.:BCC8086
CAS No.:77307-50-7
- Hirsutine
Catalog No.:BCN2758
CAS No.:7729-23-9
- Edelfosine
Catalog No.:BCC7537
CAS No.:77286-66-9
- Fmoc-Nle-OH.
Catalog No.:BCC3298
CAS No.:77284-32-3
- Zederone
Catalog No.:BCN3524
CAS No.:7727-79-9
- Abyssinone V
Catalog No.:BCN6825
CAS No.:77263-11-7
- Erythrabyssin II
Catalog No.:BCN4828
CAS No.:77263-06-0
- MG 624
Catalog No.:BCC7028
CAS No.:77257-42-2
- Carboxyatractyloside
Catalog No.:BCN2880
CAS No.:77228-71-8
- Nefiracetam
Catalog No.:BCC4504
CAS No.:77191-36-7
- Rheediaxanthone A
Catalog No.:BCN7411
CAS No.:77181-97-6
- Acetylaconitine
Catalog No.:BCN2407
CAS No.:77181-26-1
- Acamprosate calcium
Catalog No.:BCC1327
CAS No.:77337-73-6
- Triacetylpseurotin A
Catalog No.:BCN6916
CAS No.:77353-57-2
- Drimiopsin C
Catalog No.:BCN4325
CAS No.:773850-90-1
- Drimiopsin D
Catalog No.:BCN4326
CAS No.:773850-91-2
- Sesartemin
Catalog No.:BCN4779
CAS No.:77394-27-5
- Episesartemin A
Catalog No.:BCN7239
CAS No.:77449-31-1
- 5-Androsten-3β-ol-17-one ethyleneketal
Catalog No.:BCC8738
CAS No.:7745-40-6
- KM 11060
Catalog No.:BCC7578
CAS No.:774549-97-2
- Pimobendan hydrochloride
Catalog No.:BCC4175
CAS No.:77469-98-8
- Phenylpiracetam
Catalog No.:BCC1859
CAS No.:77472-70-9
- DL-m-Tyrosine
Catalog No.:BCC3332
CAS No.:775-06-4
- PTC124 (Ataluren)
Catalog No.:BCC3881
CAS No.:775304-57-9
Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages.[Pubmed:16226032]
Bioorg Med Chem. 2006 Jan 15;14(2):456-63.
The methanolic extract (200 mg/kg, p.o. and i.p.), principal coumarin constituents (isoepoxypteryxin, anomalin, and praeroside IV), and a polyacetylene constituent (falcarindiol) (25 mg/kg, i.p.) from the roots of Angelica furcijuga protected the liver injury induced by D-galactosamine (D-GalN)/lipopolysaccharide (LPS) in mice. In in vitro experiments, coumarin constituents (hyuganins A-D, anomalin, pteryxin, isopteryxin, and suksdorfin) and polyacetylene constituents [(-)-falcarinol and falcarindiol] substantially inhibited LPS-induced NO and/or TNF-alpha production in mouse peritoneal macrophages, and isoepoxypteryxin inhibited D-GalN-induced cytotoxicity in primary cultured rat hepatocytes. Furthermore, hyuganin A, anomalin, and isopteryxin inhibited the decrease in cell viability by TNF-alpha in L929 cells.
Efficient Isolation of Dihydropyranocoumarins and Simple Coumarins from Mutellina purpurea Fruits.[Pubmed:27286335]
Planta Med. 2016 Jul;82(11-12):1105-9.
For the first time, the separation of coumarin derivatives from the petroleum ether extract of the fruits of Mutellina purpurea through high-performance countercurrent chromatography (HPCCC) is described. Four compounds, pteryxin (1; 2.72 mg), hyuganin C (2; 7.94 mg), osthol (3; 4.30 mg), and hyuganin A (4; 3.09 mg), were obtained in a single run following the injection of crude extract (300 mg). Additionally, auraptenol (5) and Hyuganin D (6) were identified using LC-ESI-(Q)TOF-MS. The structures of the isolated compounds were elucidated through spectroscopic (NMR and MS) methods. This is apparently the first report of the identification of dihydropyranocoumarins in this plant, and the first time that HPCCC was used to separate them.
