(+)-Pteryxin

CAS# 13161-75-6

(+)-Pteryxin

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(+)-Pteryxin: 5mg $40 In Stock
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Quality Control of (+)-Pteryxin

Number of papers citing our products

Chemical structure

(+)-Pteryxin

3D structure

Chemical Properties of (+)-Pteryxin

Cas No. 13161-75-6 SDF Download SDF
PubChem ID 5281425 Appearance White powder
Formula C21H22O7 M.Wt 386.4
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility >17.1mg/mL in DMSO
Chemical Name [(9R,10R)-9-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-10-yl] (Z)-2-methylbut-2-enoate
SMILES CC=C(C)C(=O)OC1C(C(OC2=C1C3=C(C=C2)C=CC(=O)O3)(C)C)OC(=O)C
Standard InChIKey LYUZYPKZQDYMEE-YRCPKEQFSA-N
Standard InChI InChI=1S/C21H22O7/c1-6-11(2)20(24)27-18-16-14(28-21(4,5)19(18)25-12(3)22)9-7-13-8-10-15(23)26-17(13)16/h6-10,18-19H,1-5H3/b11-6-/t18-,19-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of (+)-Pteryxin

1 Peucedanum sp.

Biological Activity of (+)-Pteryxin

Description(+)-Pteryxin has muscle-relaxant props, it also shows hepatoprotective and nitric oxide prodn. inhibitory activity.
TargetsNO

Protocol of (+)-Pteryxin

Structure Identification
Chemistry of Natural Compounds.2008 Sep;44(5):578-581.

Plant Coumarins. 3. (+)-PTeryxin from Peucedanum terebinthaceum.[Reference: WebLink]

The potentially medically valuable pyranocoumarin (+)-Pteryxin was isolated for the first time from Peucedanum terebinthaceum Fischer et Turcz.
METHODS AND RESULTS:
The structure of (+)-Pteryxin was rigorously proved using mass spectrometry, NMR, IR, and UV spectroscopy and comparison of the spectral characteristics of this compound and its basic hydrolysis products (+)-cis- and (−)-trans-khellactone and angelic and acetic acids.

(+)-Pteryxin Dilution Calculator

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(+)-Pteryxin Molarity Calculator

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Preparing Stock Solutions of (+)-Pteryxin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.588 mL 12.94 mL 25.8799 mL 51.7598 mL 64.6998 mL
5 mM 0.5176 mL 2.588 mL 5.176 mL 10.352 mL 12.94 mL
10 mM 0.2588 mL 1.294 mL 2.588 mL 5.176 mL 6.47 mL
50 mM 0.0518 mL 0.2588 mL 0.5176 mL 1.0352 mL 1.294 mL
100 mM 0.0259 mL 0.1294 mL 0.2588 mL 0.5176 mL 0.647 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on (+)-Pteryxin

Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum.[Pubmed:8821432]

Phytochemistry. 1996 Feb;41(2):525-30.

Four new khellactone esters, (-)-trans-3'-acetyl-4'-senecioylkhellactone, (+-)-cis-3'-acetyl-4'-tigloylkhellactone, (+-)-cis-4-tigloylkhellactone, (+)-trans-4'-tigloylkhellactone, together with 14 known coumarins, isoimperatorin, psoralen, bergapten, xanthotoxol, cnidilin, (-)-selinidin, (-)-deltoin, (+)-Pteryxin, (+)-peucedanocoumarin III, xanthotoxin, imperatorin, (+)-marmesin, (+)-oxypeucedanin hydrate, (+)-peucedanol and three chromones, eugenin, (-)-hamaudol, (+)-visamminol, have been isolated from the root of Formosan Peucedanum japonicum. The structures of the new compounds were elucidated by spectral data. The identities of (+)-trans-3'-tigloyl-4'-acetylkhellactone, formerly reported as a new compound, and (+)-cis-3'-angeloyl-4'-acetyl-khellactone, with the known (+)-peucedanocoumarin III and (+)-Pteryxin, respectively, are discussed. Among the isolates, seven compounds, eugenin, (-)-selinidin, (+)-Pteryxin, imperatorin, bergapten, cnidilin and (+)-visamminol, show strong antiplatelet aggregation activity in vitro.

Description

Pteryxin, a coumarin in Peucedanum japonicum Thunb leaves, exerts antiobesity activity. Pteryxin is a potent butyrylcholinesterase (BChE) inhibitor, with an IC50 of 12.96 μg/ml.

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