Rubroside GCAS# 227597-42-4 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 227597-42-4 | SDF | Download SDF |
| PubChem ID | 100966788 | Appearance | Red powder |
| Formula | C33H38Cl2N2O9 | M.Wt | 677.58 |
| Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-[(2S,4E)-4-[(2E,4E,6E,8E,10Z,12E,14Z,16E)-11-chloro-17-[(2S,3S,5R)-3-chloro-5-methyloxolan-2-yl]-1-hydroxyheptadeca-2,4,6,8,10,12,14,16-octaenylidene]-3,5-dioxo-1-[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]pyrrolidin-2-yl]acetamide | ||
| SMILES | CC1CC(C(O1)C=CC=CC=CC(=CC=CC=CC=CC=CC(=C2C(=O)C(N(C2=O)C3C(C(C(CO3)O)O)O)CC(=O)N)O)Cl)Cl | ||
| Standard InChIKey | HQSONZSAXNUXGI-RBJMWSPMSA-N | ||
| Standard InChI | InChI=1S/C33H38Cl2N2O9/c1-20-17-22(35)26(46-20)16-12-8-7-10-14-21(34)13-9-5-3-2-4-6-11-15-24(38)28-29(41)23(18-27(36)40)37(32(28)44)33-31(43)30(42)25(39)19-45-33/h2-16,20,22-23,25-26,30-31,33,38-39,42-43H,17-19H2,1H3,(H2,36,40)/b3-2+,6-4+,8-7-,9-5+,14-10+,15-11+,16-12+,21-13-,28-24+/t20-,22+,23+,25-,26+,30+,31-,33-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Rubroside G may show antifungal activity against Aspergillus fumigatus and Candida albicans. |
| Targets | Antifection |
Rubroside G Dilution Calculator
Rubroside G Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.4758 mL | 7.3792 mL | 14.7584 mL | 29.5168 mL | 36.896 mL |
| 5 mM | 0.2952 mL | 1.4758 mL | 2.9517 mL | 5.9034 mL | 7.3792 mL |
| 10 mM | 0.1476 mL | 0.7379 mL | 1.4758 mL | 2.9517 mL | 3.6896 mL |
| 50 mM | 0.0295 mL | 0.1476 mL | 0.2952 mL | 0.5903 mL | 0.7379 mL |
| 100 mM | 0.0148 mL | 0.0738 mL | 0.1476 mL | 0.2952 mL | 0.369 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Rubrosides A−H, New Bioactive Tetramic Acid Glycosides from the Marine Sponge Siliquariaspongia japonica1
J. Org. Chem., 1999, 64 (7):2331–9.
Eight new tetramic acid glycosides named rubrosides A-H(rubroside A,rubroside B, rubroside C, rubroside D, rubroside E, rubroside F, Rubroside G, rubroside H) have been isolated from the marine sponge Siliquariaspongia japonica. Their structures were elucidated on the basis of spectral data as tetramic acid glycosides containing polyenes terminating in a 4-chloro-2-methyltetrahydrofuran ring. The absolute stereochemistry of the furan functionality in the two major metabolites, rubrosides D and F, was determined by the NMR method using chiral anisotropic reagents for tetrahydro-2-furoic acid derived by RuO4 oxidation. The absolute stereochemistry of tetramic acid and of the sugar moieties in all rubrosides was deduced by chiral GC analysis of chemical degradation products. The rubrosides induced numerous large intracellular vacuoles in 3Y1 rat fibroblasts at concentrations of 0.5−1.0 μg/mL, and rubrosides A, C, D, and E were cytotoxic against P388 murine leukemia cells with IC50 values of 0.046−0.21 μg/mL. Most rubrosides show antifungal activity against Aspergillus fumigatus and Candida albicans.
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