S-(5'-Adenosyl)-L-methionine chlorideCAS# 24346-00-7 |
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| Cas No. | 24346-00-7 | SDF | Download SDF |
| PubChem ID | 90473 | Appearance | Powder |
| Formula | C15H23ClN6O5S | M.Wt | 434.9 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium;chloride | ||
| SMILES | C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.[Cl-] | ||
| Standard InChIKey | DYFPQIYEZQULMZ-XKGORWRGSA-N | ||
| Standard InChI | InChI=1S/C15H22N6O5S.ClH/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);1H/t7-,8+,10+,11+,14+,27?;/m0./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Targets | Histone Methyltransferase |
S-(5'-Adenosyl)-L-methionine chloride Dilution Calculator
S-(5'-Adenosyl)-L-methionine chloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2994 mL | 11.4969 mL | 22.9938 mL | 45.9876 mL | 57.4845 mL |
| 5 mM | 0.4599 mL | 2.2994 mL | 4.5988 mL | 9.1975 mL | 11.4969 mL |
| 10 mM | 0.2299 mL | 1.1497 mL | 2.2994 mL | 4.5988 mL | 5.7484 mL |
| 50 mM | 0.046 mL | 0.2299 mL | 0.4599 mL | 0.9198 mL | 1.1497 mL |
| 100 mM | 0.023 mL | 0.115 mL | 0.2299 mL | 0.4599 mL | 0.5748 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Amperometric sensing of norepinephrine at picomolar concentrations using screen printed, high surface area mesoporous carbon.[Pubmed:23845478]
Anal Chim Acta. 2013 Jul 25;788:32-8.
Norepinephrine (NE) is detected amperometrically using the enzyme Phenylethanolamine N-methyl transferase and cofactor S-(5'-Adenosyl)-l-methionine chloride dihydrochloride with disposable screen printed mesoporous carbon electrodes. The role of internal surface area and pore size of the mesoporous carbon is systematically examined using soft-templated, mesoporous silica-carbon powders with highly microporous walls obtained from etching of the silica to produce powders with surface areas ranging from 671-2339 m(2)g(-1). As the surface area increases, the sensitivity of the biosensor at very low NE concentrations (0-500 pg mL(-1)) in phosphate buffered saline (PBS) increases just as the current signal increases with respect to the NE concentration of 81-1581 muA mL ng(-1) cm(-2) for the mesoporous carbons. The best performing electrode provides similar sensitivity in whole rabbit blood in comparison to PBS despite no membrane layer to filter the non-desired reactants; the small (<5 nm) pore size and large internal surface area acts to minimize non-specific events that decrease sensitivity.
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