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Saprorthoquinone

CAS# 102607-41-0

Saprorthoquinone

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Quality Control of Saprorthoquinone

Number of papers citing our products

Chemical structure

Saprorthoquinone

3D structure

Chemical Properties of Saprorthoquinone

Cas No. 102607-41-0 SDF Download SDF
PubChem ID 372741 Appearance Powder
Formula C20H24O2 M.Wt 296.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-methyl-8-(4-methylpent-3-enyl)-3-propan-2-ylnaphthalene-1,2-dione
SMILES CC1=C(C2=C(C=C1)C=C(C(=O)C2=O)C(C)C)CCC=C(C)C
Standard InChIKey FWJDKZSXXFWHPR-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H24O2/c1-12(2)7-6-8-16-14(5)9-10-15-11-17(13(3)4)19(21)20(22)18(15)16/h7,9-11,13H,6,8H2,1-5H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Saprorthoquinone

The roots of Salvia prionitis

Biological Activity of Saprorthoquinone

DescriptionSaprorthoquinone is a natural product from Salvia prionitis.
In vitro

Cytotoxic Activity of Diterpenoids Isolated from Salvia hypargeia[Reference: WebLink]

Pharmaceutical Biology, 1999 , 37 (2) :148-151.

Ten diterpenoids [6a-hydroxysalvinolone ( 1 ), 6a-hydroxytaxodone ( 2 ), aethiopinone ( 3 ), microstegiol ( 4 ), ferruginol ( 5 ), Saprorthoquinone ( 6 ), 11,12-dioxoabieta-8,13-diene ( 7 ), taxodione ( 8 ), hypargenin A ( 9 ), hypargenin D ( 10 )] and three triterpenoids [lupeol 3-acetate, d-oleanol 3-acetate and -sitosterol] were isolated from the roots of Salvia hypargeia , a plant endemic to Turkey.
METHODS AND RESULTS:
The crude extract and compounds 1-2 , 5-10 were tested against a panel of human cancer cell lines [human breast cancer (BC 1), human lung cancer (LU 2), human colon cancer (COL 2), human epidermoidal carcinoma in mouth (KB), vinblastine-resistant KB-VI, hormone-dependent human prostate cancer (LNCaP)] as well as P388 and ASK cells in culture.
CONCLUSIONS:
The crude extract was active in all of the test systems, except KB. Isolates 1 and 8 were also found to mediate a generalized cytotoxic response.

Saprorthoquinone Dilution Calculator

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Saprorthoquinone Molarity Calculator

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Preparing Stock Solutions of Saprorthoquinone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3738 mL 16.8691 mL 33.7382 mL 67.4764 mL 84.3455 mL
5 mM 0.6748 mL 3.3738 mL 6.7476 mL 13.4953 mL 16.8691 mL
10 mM 0.3374 mL 1.6869 mL 3.3738 mL 6.7476 mL 8.4345 mL
50 mM 0.0675 mL 0.3374 mL 0.6748 mL 1.3495 mL 1.6869 mL
100 mM 0.0337 mL 0.1687 mL 0.3374 mL 0.6748 mL 0.8435 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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