Sequosempervirin BCAS# 864719-17-5 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 864719-17-5 | SDF | Download SDF |
| PubChem ID | 70698191 | Appearance | Powder |
| Formula | C18H20O5 | M.Wt | 316.4 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (E,2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)pent-4-ene-1,2-diol | ||
| SMILES | COC1=C(C=CC(=C1)C(C=CC2=CC=C(C=C2)O)C(CO)O)O | ||
| Standard InChIKey | JRWXFOFDIRHTQG-GRNKITJOSA-N | ||
| Standard InChI | InChI=1S/C18H20O5/c1-23-18-10-13(5-9-16(18)21)15(17(22)11-19)8-4-12-2-6-14(20)7-3-12/h2-10,15,17,19-22H,11H2,1H3/b8-4+/t15-,17+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Sequosempervirin B is a natural product from Sequoia sempervirens. |
| In vitro | Norlignans from Sequoia sempervirens.[Pubmed: 17191998 ]Chem Biodivers. 2005 Apr;2(4):497-505.
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Sequosempervirin B Dilution Calculator
Sequosempervirin B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1606 mL | 15.8028 mL | 31.6056 mL | 63.2111 mL | 79.0139 mL |
| 5 mM | 0.6321 mL | 3.1606 mL | 6.3211 mL | 12.6422 mL | 15.8028 mL |
| 10 mM | 0.3161 mL | 1.5803 mL | 3.1606 mL | 6.3211 mL | 7.9014 mL |
| 50 mM | 0.0632 mL | 0.3161 mL | 0.6321 mL | 1.2642 mL | 1.5803 mL |
| 100 mM | 0.0316 mL | 0.158 mL | 0.3161 mL | 0.6321 mL | 0.7901 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Norlignans from Sequoia sempervirens.[Pubmed:17191998]
Chem Biodivers. 2005 Apr;2(4):497-505.
Six new norlignans, named sequosempervirins B-G (1-6), together with three known norlignans, agatharesinol (7), agatharesinol acetonide (8), and sugiresinol (9), were isolated from the branches and leaves of Sequoia sempervirens. Their structures were determined mainly by high-resolution mass spectroscopy (HR-MS), and various 1D- and 2D-NMR methods, as well as, in the case of 1, by means of X-ray diffraction. Compound 8 showed anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM). The acetone extract of S. sempervirens was found to be antifungal towards Candida glabrata (IC50 = 15.98 microg/ml), and both the acetone and MeOH extracts inhibited the proteolytic activity of cathepsin B (IC50 = 4.58 and 5.49 microg/ml, resp.).
