Gelsempervine ACAS# 865187-17-3 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 865187-17-3 | SDF | Download SDF |
| PubChem ID | 131636659 | Appearance | Powder |
| Formula | C22H26N2O4 | M.Wt | 382.5 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | methyl (1S,14S,15E,18R)-15-ethylidene-18-(hydroxymethyl)-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate | ||
| SMILES | CC=C1CN(C2CC3=C(C(=O)CC1C2(CO)C(=O)OC)NC4=CC=CC=C34)C | ||
| Standard InChIKey | CZRUSFCSECMUDS-VQHRILDESA-N | ||
| Standard InChI | InChI=1S/C22H26N2O4/c1-4-13-11-24(2)19-9-15-14-7-5-6-8-17(14)23-20(15)18(26)10-16(13)22(19,12-25)21(27)28-3/h4-8,16,19,23,25H,9-12H2,1-3H3/b13-4-/t16-,19-,22+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Gelsempervine A is a natural product from Gelsemium elegans. |
| Structure Identification | Symposium on the chemistry of natural products, 2006 (48) :319-324.New Indole Alkaloids from Gelsemium Plants and their Cytotoxic Activity on Tumor Cells[Reference: WebLink]Gelseiridone (10) is a new type of alkaloid having a nitrogen-carbon linkage between a gelsenicine-type monoterpenoid indole alkaloid that possesses an α,β-unsaturated ketone residue as well as the N_b-C20 seco-form and a monoterpene unit having an iridoid skeleton.
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Gelsempervine A Dilution Calculator
Gelsempervine A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6144 mL | 13.0719 mL | 26.1438 mL | 52.2876 mL | 65.3595 mL |
| 5 mM | 0.5229 mL | 2.6144 mL | 5.2288 mL | 10.4575 mL | 13.0719 mL |
| 10 mM | 0.2614 mL | 1.3072 mL | 2.6144 mL | 5.2288 mL | 6.5359 mL |
| 50 mM | 0.0523 mL | 0.2614 mL | 0.5229 mL | 1.0458 mL | 1.3072 mL |
| 100 mM | 0.0261 mL | 0.1307 mL | 0.2614 mL | 0.5229 mL | 0.6536 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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New Indole Alkaloids from Gelsemium Plants and their Cytotoxic Activity on Tumor Cells
Symposium on the chemistry of natural products, 2006 (48) :319-324.
Gelseiridone (10) is a new type of alkaloid having a nitrogen-carbon linkage between a gelsenicine-type monoterpenoid indole alkaloid that possesses an α,β-unsaturated ketone residue as well as the N_b-C20 seco-form and a monoterpene unit having an iridoid skeleton. Five new sarpagine-type alkaloids, Gelsempervine A (23), gelsempervine B (24), gelsempervine C (25), and gelsempervine D (26), and 19Z-16-epi-voacarpine (27), and one yohimbane-type alkaloid, sempervilam (29) were isolated from G. sempervirens. Spectroscopic data suggest that 23 existed as a C/D ring-opening structure with the keto-amine form (A) in such aprotic solvents as CH3CN, and as a transannular structure with the zwitterionic form (B) in such protic solvents as CH3OH.
