Spiramine A

CAS# 114531-28-1

Spiramine A

Catalog No. BCN6023----Order now to get a substantial discount!

Product Name & Size Price Stock
Spiramine A: 5mg $989 In Stock
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Quality Control of Spiramine A

Number of papers citing our products

Chemical structure

Spiramine A

3D structure

Chemical Properties of Spiramine A

Cas No. 114531-28-1 SDF Download SDF
PubChem ID 441757 Appearance Powder
Formula C24H33NO4 M.Wt 399.5
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(=O)OC1C(=C)C2CCC13C(C2)C45CCCC6(C4CC3OC5N7C6OCC7)C
Standard InChIKey ZPELMDXCJZDIBP-OWOZRORESA-N
Standard InChI InChI=1S/C24H33NO4/c1-13-15-5-8-24(19(13)28-14(2)26)17(11-15)23-7-4-6-22(3)16(23)12-18(24)29-21(23)25-9-10-27-20(22)25/h15-21H,1,4-12H2,2-3H3/t15-,16+,17-,18+,19-,20+,21+,22+,23-,24+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Spiramine A

The herbs of Spiraea japonica

Biological Activity of Spiramine A

DescriptionStandard reference
In vitro

Approach to the biosynthesis of atisine-type diterpenoid alkaloids.[Pubmed: 19275222]

J Nat Prod. 2009 Apr;72(4):645-9.


METHODS AND RESULTS:
To determine the biosynthesis pathway of the atisine-type diterpenoid alkaloids Spiramine A/B and C/D, feeding experiments in in vitro cultured plantlets and enzymatic transformations in cell-free extracts were performed in combination with LCMS and tandem MS analyses. L-[2-(13)C,(15)N]Serine was used in the feeding experiments and enzymatic transformations, and the diterpene spiraminol was identified as a biosynthetic precursor of Spiramine Alkaloids. The LCMS and tandem MS spectra of the extracts from these experiments indicated that L-[2-(13)C,(15)N]serine was incorporated into Spiramine A/B and C/D.
CONCLUSIONS:
The labeled reaction products show that l-serine is the one possible nitrogen source involved in the biosynthesis of atisine-type DAs.

Spiramine A Dilution Calculator

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Spiramine A Molarity Calculator

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Preparing Stock Solutions of Spiramine A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5031 mL 12.5156 mL 25.0313 mL 50.0626 mL 62.5782 mL
5 mM 0.5006 mL 2.5031 mL 5.0063 mL 10.0125 mL 12.5156 mL
10 mM 0.2503 mL 1.2516 mL 2.5031 mL 5.0063 mL 6.2578 mL
50 mM 0.0501 mL 0.2503 mL 0.5006 mL 1.0013 mL 1.2516 mL
100 mM 0.025 mL 0.1252 mL 0.2503 mL 0.5006 mL 0.6258 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Spiramine A

Approach to the biosynthesis of atisine-type diterpenoid alkaloids.[Pubmed:19275222]

J Nat Prod. 2009 Apr;72(4):645-9.

To determine the biosynthesis pathway of the atisine-type diterpenoid alkaloids spiramines A/B and C/D, feeding experiments in in vitro cultured plantlets and enzymatic transformations in cell-free extracts were performed in combination with LCMS and tandem MS analyses. L-[2-(13)C,(15)N]Serine was used in the feeding experiments and enzymatic transformations, and the diterpene spiraminol was identified as a biosynthetic precursor of Spiramine Alkaloids. The LCMS and tandem MS spectra of the extracts from these experiments indicated that L-[2-(13)C,(15)N]serine was incorporated into spiramines A/B and C/D. The labeled reaction products show that l-serine is the one possible nitrogen source involved in the biosynthesis of atisine-type DAs.

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