Boeravinone BCAS# 114567-34-9 |
Quality Control & MSDS
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| Cas No. | 114567-34-9 | SDF | Download SDF |
| PubChem ID | 14018348 | Appearance | Yellow powder |
| Formula | C17H12O6 | M.Wt | 312.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in acetone and methanol; insoluble in water | ||
| Chemical Name | 6,9,11-trihydroxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one | ||
| SMILES | CC1=C(C=C2C(=C1O)C(=O)C3=C(O2)C(OC4=CC=CC=C43)O)O | ||
| Standard InChIKey | YVVDYYFGAWQOGB-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H12O6/c1-7-9(18)6-11-13(14(7)19)15(20)12-8-4-2-3-5-10(8)23-17(21)16(12)22-11/h2-6,17-19,21H,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Boerhaavia coccinea
| Description | 1. Boeravinone B exhibits significant anti-inflammatory activity (56.6% at 50 mg/kg) when evaluated in an in vivo carrageenan-induced rat paw model. 2. Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for further development. |
| Targets | Antifection | COX |
Boeravinone B Dilution Calculator
Boeravinone B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.202 mL | 16.0102 mL | 32.0205 mL | 64.041 mL | 80.0512 mL |
| 5 mM | 0.6404 mL | 3.202 mL | 6.4041 mL | 12.8082 mL | 16.0102 mL |
| 10 mM | 0.3202 mL | 1.601 mL | 3.202 mL | 6.4041 mL | 8.0051 mL |
| 50 mM | 0.064 mL | 0.3202 mL | 0.6404 mL | 1.2808 mL | 1.601 mL |
| 100 mM | 0.032 mL | 0.1601 mL | 0.3202 mL | 0.6404 mL | 0.8005 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Rotenoids from Boerhaavia diffusa as potential anti-inflammatory agents.[Pubmed:23914900]
J Nat Prod. 2013 Aug 23;76(8):1393-8.
Five new (2, 3, 5, 7, and 9) and four known rotenoids (1, 4, 6, and 8) were isolated from a methanol extract of Boerhaavia diffusa roots. The structures of the new rotenoids were elucidated by spectroscopic data interpretation. The 70% ethanol extract, a rotenoid-rich fraction, and all isolated rotenoids were evaluated for their COX-1 and COX-2 inhibitory activities. Among the rotenoids tested, compound 7 showed the most potent COX-1 and COX-2 inhibition, with IC(5)(0) values of 21.7 +/- 0.5 and 25.5 +/- 0.6 muM, respectively. Boeravinone B (6) exhibited significant anti-inflammatory activity (56.6% at 50 mg/kg) when evaluated in an in vivo carrageenan-induced rat paw model.
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