Sudan II

CAS# 3118-97-6

Sudan II

2D Structure

Catalog No. BCN8383----Order now to get a substantial discount!

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3D structure

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Sudan II

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Chemical Properties of Sudan II

Cas No. 3118-97-6 SDF Download SDF
PubChem ID 5809936 Appearance Brown red crystal
Formula C18H16N2O M.Wt 276.33
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1Z)-1-[(2,4-dimethylphenyl)hydrazinylidene]naphthalen-2-one
SMILES CC1=CC(=C(C=C1)NN=C2C(=O)C=CC3=CC=CC=C32)C
Standard InChIKey YPXOPAFVVHXQDP-ZZEZOPTASA-N
Standard InChI InChI=1S/C18H16N2O/c1-12-7-9-16(13(2)11-12)19-20-18-15-6-4-3-5-14(15)8-10-17(18)21/h3-11,19H,1-2H3/b20-18-
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Sudan II Dilution Calculator

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Sudan II Molarity Calculator

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Preparing Stock Solutions of Sudan II

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6189 mL 18.0943 mL 36.1886 mL 72.3772 mL 90.4715 mL
5 mM 0.7238 mL 3.6189 mL 7.2377 mL 14.4754 mL 18.0943 mL
10 mM 0.3619 mL 1.8094 mL 3.6189 mL 7.2377 mL 9.0472 mL
50 mM 0.0724 mL 0.3619 mL 0.7238 mL 1.4475 mL 1.8094 mL
100 mM 0.0362 mL 0.1809 mL 0.3619 mL 0.7238 mL 0.9047 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Sudan II

Simultaneous determination of twelve dyes in meat products: Development and validation of an analytical method based on HPLC-UV-diode array detection.[Pubmed:30797322]

Food Chem. 2019 Jul 1;285:1-9.

The use of food dyes in meat is subject to regulations, due to food safety concerns. A reliable method for the determination of 12 food dyes (Amaranth, Ponceau 4R, Carmine, Ponceau SX, Ponceau 3R, Allura Red AC, Carmoisine, Erythrosine, Sudan I, Sudan II, Sudan III and Sudan IV) in meat products using high performance liquid chromatography coupled to UV-diode array detection was developed, optimized and fully validated. The extraction was accomplished using acetonitrile, methanol, water, ammonia, 50:40:9:1 (v/v/v/v) as the solvent, and an ultrasonic bath. Chromatographic separation was achieved using a C18 RP column and samples eluted with a gradient acetate-acetonitrile mobile phase. Good analytical performance was obtained, in terms of selectivity, sensitivity, accuracy and ruggedness. Both method precision (CV% range: 6.2%-18.0%) and recovery (range: 86.4%-105.0%) complied with Decision 657/2002/EC, suggesting the procedure could be applied successfully for analyses of meat products in the European Union.

Chemometrics-assisted determination of Sudan dyes using zinc oxide nanoparticle-based electrochemical sensor.[Pubmed:30722927]

Food Chem. 2019 Jun 15;283:68-72.

Multivariate curve resolution-alternating least squares (MCR-ALS) assisted with electrochemical techniques was applied for simultaneous determination of Sudan II and III at a surface of zinc oxide nanoparticles (ZnONPs) modified carbon paste electrode. Characterization of the ZnONPs and the nanostructured modified electrode was performed by X-ray diffraction (XRD), scanning electron microscopy (SEM), electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) techniques. Response surface methodology using central composite rotatable design was employed to design of experiments and achieving to optimum values of variables. For simultaneous determination of Sudan II and III, electrochemical second order data were obtained by changing of pulse height in differential pulse voltammetry technique. MCR-ALS was performed on the data to obtain the decomposition peaks of analytes. Then, the detection limits were obtained 1.87 and 2.62nM for Sudan II and III, respectively. Finally, this method used for the analysis of the two analytes in real samples.

Ultrasensitive detection of Sudan I in food samples by a quantitative immunochromatographic assay.[Pubmed:30502190]

Food Chem. 2019 Mar 30;277:595-603.

An immunochromatographic assay (ICA) based on surface-enhanced Raman scattering (SERS) for ultrasensitive determination of Sudan I in food samples was reported. Gold-silver core-shell bimetallic nanorods (referred to as Au@Ag NRs) were synthesized, characterized and used as the substrate for preparation of the ICA. Polyclonal antibody against Sudan I was immobilized on the surface of the Au@Ag NRs carrying the Raman reporter 5,5'-dithiobis (2-nitrobenzoic acid). The Raman scattering intensity on the test line was used for quantitation of Sudan I. The assay was completed in 15min. IC50 and limit of detection (LOD) were 30pgmL(-1) and 0.2pgmL(-1), respectively. There was no cross-reactivity (CR) of the assay with Sunset Yellow, Lemon Yellow and Brilliant blue FCF, but only 3.53%-9.74% CR with Sudan II, III and IV. The recoveries of Sudan I from spiked food samples were in the range of 88.9-107.6% with relative standard deviation of 3.7-8.7% (n=3).

Extractive Spectrophotometric Determination of Nortriptyline Hydrochloride Using Sudan II, IV and Black B.[Pubmed:28817110]

Sci Pharm. 2017 Aug 17;69(2):140-149.

A simple spectrophotometric methods has been developed for the determination of nortriptyline hydrochloride in pure and in pharmaceuticalformulations based on the formation of ion-pair complexes with sudun II (SII), sudan (IV) (SIV) and sudan black B (SBB). The selectivity of the method was improved through extraction with chloroform. The optimum conditions for complete extracted colour development were assessed. The absorbance measurements were made at 534, 596 and 649 nm for SII, SIV and SBB complexes, respectively. The calibration graph was linear in the ranges 0.5- 280. 0.5- 37.5 and 0.5 - 31.0 mug ml(-1) of the drug usiny the same reagents, respectively. The precision of the procedure was checked by calculating the relative standard deviation of ten replicate determinations on 15 mug ml(-1) of nortriptyline HCI and was found to be 1.7, 1.3 and 1.55% using SII, SIV, and SBB complexes, respectively. The molar absorptivity and Sandell sensitivity for each ion-pair were calculated. The proposed methods were successfully applied to the deterniination of pure nortriptyline HCI and in pharmaceutical formulations, and the results demonstrated that the method is equally accurate, precise and reproducible as the official method.

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