CedeodarinCAS# 31076-39-8 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 31076-39-8 | SDF | Download SDF |
| PubChem ID | 442419 | Appearance | Powder |
| Formula | C16H14O7 | M.Wt | 318.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Synonyms | 6-Methyldihydroquercetin;Methyldihydroquercetin | ||
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-6-methyl-2,3-dihydrochromen-4-one | ||
| SMILES | CC1=C(C=C2C(=C1O)C(=O)C(C(O2)C3=CC(=C(C=C3)O)O)O)O | ||
| Standard InChIKey | KPCWWZLBHGSXPW-JKSUJKDBSA-N | ||
| Standard InChI | InChI=1S/C16H14O7/c1-6-9(18)5-11-12(13(6)20)14(21)15(22)16(23-11)7-2-3-8(17)10(19)4-7/h2-5,15-20,22H,1H3/t15-,16+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Standard reference |
| Structure Identification | Adv Bioinformatics. 2014;2014:903246.Pharmacophore Modeling and Molecular Docking Studies on Pinus roxburghii as a Target for Diabetes Mellitus.[Pubmed: 25114678]The present study attempts to establish a relationship between ethnopharmacological claims and bioactive constituents present in Pinus roxburghii against all possible targets for diabetes through molecular docking and to develop a pharmacophore model for the active target.
Planta Med. 1981 Sep;43(1):82-5.Dihydroflavanonols from Cedrus deodara, A (13)C NMR study.[Pubmed: 17402014]
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Cedeodarin Dilution Calculator
Cedeodarin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1417 mL | 15.7085 mL | 31.4169 mL | 62.8338 mL | 78.5423 mL |
| 5 mM | 0.6283 mL | 3.1417 mL | 6.2834 mL | 12.5668 mL | 15.7085 mL |
| 10 mM | 0.3142 mL | 1.5708 mL | 3.1417 mL | 6.2834 mL | 7.8542 mL |
| 50 mM | 0.0628 mL | 0.3142 mL | 0.6283 mL | 1.2567 mL | 1.5708 mL |
| 100 mM | 0.0314 mL | 0.1571 mL | 0.3142 mL | 0.6283 mL | 0.7854 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Dihydroflavanonols from Cedrus deodara, A (13)C NMR study.[Pubmed:17402014]
Planta Med. 1981 Sep;43(1):82-5.
High resolution (13)C NMR study of taxifolin, Cedeodarin, cedrin and their methyl ethers allowed unambiguous placement of the Me in 5,7-dihydroxyflavanonol nucleus, besides providing other valuable information on the substitution pattern in the molecule.
Pharmacophore Modeling and Molecular Docking Studies on Pinus roxburghii as a Target for Diabetes Mellitus.[Pubmed:25114678]
Adv Bioinformatics. 2014;2014:903246.
The present study attempts to establish a relationship between ethnopharmacological claims and bioactive constituents present in Pinus roxburghii against all possible targets for diabetes through molecular docking and to develop a pharmacophore model for the active target. The process of molecular docking involves study of different bonding modes of one ligand with active cavities of target receptors protein tyrosine phosphatase 1-beta (PTP-1beta), dipeptidyl peptidase-IV (DPP-IV), aldose reductase (AR), and insulin receptor (IR) with help of docking software Molegro virtual docker (MVD). From the results of docking score values on different receptors for antidiabetic activity, it is observed that constituents, namely, secoisoresinol, pinoresinol, and Cedeodarin, showed the best docking results on almost all the receptors, while the most significant results were observed on AR. Then, LigandScout was applied to develop a pharmacophore model for active target. LigandScout revealed that 2 hydrogen bond donors pointing towards Tyr 48 and His 110 are a major requirement of the pharmacophore generated. In our molecular docking studies, the active constituent, secoisoresinol, has also shown hydrogen bonding with His 110 residue which is a part of the pharmacophore. The docking results have given better insights into the development of better aldose reductase inhibitor so as to treat diabetes related secondary complications.
