Taxiphyllin

CAS# 21401-21-8

Taxiphyllin

Catalog No. BCN4922----Order now to get a substantial discount!

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Taxiphyllin: 5mg $725 In Stock
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Chemical structure

Taxiphyllin

3D structure

Chemical Properties of Taxiphyllin

Cas No. 21401-21-8 SDF Download SDF
PubChem ID 107721 Appearance Powder
Formula C14H17NO7 M.Wt 311.3
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R)-2-(4-hydroxyphenyl)-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyacetonitrile
SMILES C1=CC(=CC=C1C(C#N)OC2C(C(C(C(O2)CO)O)O)O)O
Standard InChIKey NVLTYOJHPBMILU-GMDXDWKASA-N
Standard InChI InChI=1S/C14H17NO7/c15-5-9(7-1-3-8(17)4-2-7)21-14-13(20)12(19)11(18)10(6-16)22-14/h1-4,9-14,16-20H,6H2/t9-,10+,11+,12-,13+,14+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Taxiphyllin

The herbs of Pleioblastus amarus (Keng) Keng f.

Biological Activity of Taxiphyllin

Description1. Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. 2. Taxiphyllin displays mild antibacterial activity against Staphylococcus aureus.
TargetsAntifection | Tyrosinase

Taxiphyllin Dilution Calculator

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Taxiphyllin Molarity Calculator

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Preparing Stock Solutions of Taxiphyllin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2123 mL 16.0617 mL 32.1234 mL 64.2467 mL 80.3084 mL
5 mM 0.6425 mL 3.2123 mL 6.4247 mL 12.8493 mL 16.0617 mL
10 mM 0.3212 mL 1.6062 mL 3.2123 mL 6.4247 mL 8.0308 mL
50 mM 0.0642 mL 0.3212 mL 0.6425 mL 1.2849 mL 1.6062 mL
100 mM 0.0321 mL 0.1606 mL 0.3212 mL 0.6425 mL 0.8031 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Taxiphyllin

Phytochemical constituents from Salsola tetrandra.[Pubmed:16989538]

J Nat Prod. 2006 Sep;69(9):1366-9.

The new norisoprenoid 3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-d-glucopyranoside (1) and the long-chain hydroxy fatty acids 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid (2) and 9,12,13-trihydroxyoctadeca-10(E)-dienoic acid (3) were isolated from Salsola tetrandra aerial parts, together with 3,4,5-trimethoxyphenyl-beta-d-glucopyranoside (4), 9-hydroxylinaloyl glucoside (5), Taxiphyllin (6), trans-N-feruloyltyramine (7), and S-(-)-trans-N-feruloyloctopamine (8). Their structures were elucidated by extensive spectroscopic analysis and chemical methods. Compounds 6 and 8 displayed mild antibacterial activity against Staphylococcus aureus, whereas compound 6 showed the highest activity in the Artemia salina bioassay.

The in vitro biosynthesis of taxiphyllin and the channeling of intermediates in Triglochin maritima.[Pubmed:7012151]

J Biol Chem. 1981 May 10;256(9):4253-8.

The in vitro biosynthesis of the cyanogenic glucoside Taxiphyllin has recently been demonstrated in Triglochin maritima (Hosel, W., and Nahrstedt, A. (1980) Arch. Biochem. Biophys. 203, 753-757). We have now studied in more detail the multistep conversion of tyrosine into p-hydroxymandelonitrile, the immediate precursor of Taxiphyllin, catalyzed by microsomes isolated from dark-grown seedlings. The biosynthetic pathway involves N-hydroxytyrosine, p-hydroxyphenylacetaldoxime, and p-hydroxyphenylacetonitrile. In marked contrast to an analogous pathway in Sorghum bicolor, p-hydroxyphenylacetonitrile is the best substrate for cyanide production (Vmax = 224 nmol/h/g, fresh wt) and the physiological substrate tyrosine is the poorest (Vmax = 18.8 nmol/h/g, fresh wt). The substrates exhibit alkaline pH optima between 7.5 and 9, and all except tyrosine show pronounced substrate inhibition. We have found that p-hydroxyphenylacetonitrile generated in situ from tyrosine is free to equilibrate by diffusion with exogenous material. On the other hand, neither N-hydroxytyrosine nor p-hydroxyphenylacetaldoxime will readily exchange with exogenous intermediates. We consider both N-hydroxytyrosine and p-hydroxyphenylacetaldoxime to be channeled in T. maritima, whereas in S. bicolor N-hydroxytyrosine and p-hydroxyphenylacetonitrile are channeled and the aldoxime is freely exchangeable.

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