Taxuspine B

CAS# 157414-05-6

Taxuspine B

Catalog No. BCN6938----Order now to get a substantial discount!

Product Name & Size Price Stock
Taxuspine B: 5mg $1012 In Stock
Taxuspine B: 10mg Please Inquire In Stock
Taxuspine B: 20mg Please Inquire Please Inquire
Taxuspine B: 50mg Please Inquire Please Inquire
Taxuspine B: 100mg Please Inquire Please Inquire
Taxuspine B: 200mg Please Inquire Please Inquire
Taxuspine B: 500mg Please Inquire Please Inquire
Taxuspine B: 1000mg Please Inquire Please Inquire

Quality Control of Taxuspine B

Number of papers citing our products

Chemical structure

Taxuspine B

3D structure

Chemical Properties of Taxuspine B

Cas No. 157414-05-6 SDF Download SDF
PubChem ID 5321744 Appearance Powder
Formula C35H42O10 M.Wt 622.71
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1=C2C(C(=O)C3(CC(=CC(C(C2(C)C)CC1OC(=O)C)OC(=O)C)C(CC3OC(=O)C)OC(=O)C=CC4=CC=CC=C4)C)O
Standard InChIKey RWMXWLFXARITCC-CRMVJMMESA-N
Standard InChI InChI=1S/C35H42O10/c1-19-26(42-20(2)36)16-25-28(43-21(3)37)15-24-18-35(7,33(41)32(40)31(19)34(25,5)6)29(44-22(4)38)17-27(24)45-30(39)14-13-23-11-9-8-10-12-23/h8-15,25-29,32,40H,16-18H2,1-7H3/b14-13+,24-15+/t25-,26-,27-,28-,29-,32+,35-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Taxuspine B

The stems of the Japanese yew Taxus cuspidata Sieb. et Zucc.

Biological Activity of Taxuspine B

DescriptionTaxuspine B is a natural product from the Japanese yew Taxus cuspidata Sieb. et Zucc.
In vitro

Taxuspines A ~ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells[Reference: WebLink]

Tetrahedron, 1994, 50(25):7401-7416。


METHODS AND RESULTS:
Three new taxoids, taxuspine A, Taxuspine B, taxuspine C (1 ~ 3), possessing different skeletons from usual taxane diterpenoids consisting of a 6/8/6-membered ring system have been isolated together with known taxoids (4 ~ 12) from stems of the Japanese yew Taxus cuspidata Sieb. et Zucc. and the structures elucidated on the basis of spectroscopic data. Most of the taxoids increased cellular accumulation of vincristine in multidrug-resistant tumor cells, while taxol (12) did not show such an activity. The taxoids (1 ~ 11) showed no or weak cytotoxicity and among them, 2(Taxuspine B) and 6 reduced appreciably CaCI2-induced depolymerization of microtubules.
CONCLUSIONS:
These results suggest that some taxoids may be useful for overcoming multidrug resistance in tumor cells.

Taxuspine B Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Taxuspine B Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Taxuspine B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6059 mL 8.0294 mL 16.0588 mL 32.1177 mL 40.1471 mL
5 mM 0.3212 mL 1.6059 mL 3.2118 mL 6.4235 mL 8.0294 mL
10 mM 0.1606 mL 0.8029 mL 1.6059 mL 3.2118 mL 4.0147 mL
50 mM 0.0321 mL 0.1606 mL 0.3212 mL 0.6424 mL 0.8029 mL
100 mM 0.0161 mL 0.0803 mL 0.1606 mL 0.3212 mL 0.4015 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Taxuspine B

Dantaxusins A and B, two new taxoids from Taxus yunnanensis.[Pubmed:11520230]

J Nat Prod. 2001 Aug;64(8):1073-6.

Two new taxane diterpenes, dantaxusin A [5 alpha-cinnamoyloxy-2 alpha,7 beta,13 alpha-triacetoxy-2(3-->20)abeo-taxa-4(20),11-diene-9,10-dione (1)] and dantaxusin B [5 alpha-cinnamoyloxy-9 alpha-hydroxy-10 beta,13 alpha-diacetoxytaxa-4(20),11-diene (2)], were isolated from an ethanol extract of the aerial parts of Taxus yunnanensis along with Taxuspine B, 2-deacetoxytaxinine J, taxuyunnanine C, taxinine B, taxuspine C, and taxinine NN-4. The structures of 1 and 2 were established on the basis of 1D and 2D NMR and HRMS spectroscopic methods.

Keywords:

Taxuspine B,157414-05-6,Natural Products, buy Taxuspine B , Taxuspine B supplier , purchase Taxuspine B , Taxuspine B cost , Taxuspine B manufacturer , order Taxuspine B , high purity Taxuspine B

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: