Trichokaurin

CAS# 23811-50-9

Trichokaurin

2D Structure

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Trichokaurin: 5mg $828 In Stock
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Quality Control of Trichokaurin

3D structure

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Trichokaurin

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Chemical Properties of Trichokaurin

Cas No. 23811-50-9 SDF Download SDF
PubChem ID 91884741 Appearance Powder
Formula C24H34O7 M.Wt 434.5
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1R,2R,5R,7R,8R,9S,10S,11S,15R)-7-acetyloxy-9,15-dihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl] acetate
SMILES CC(=O)OC1C2C(CCC(C23COC1(C45C3CCC(C4)C(=C)C5OC(=O)C)O)O)(C)C
Standard InChIKey GLBRPJYMFLHADY-GBSGVOFLSA-N
Standard InChI InChI=1S/C24H34O7/c1-12-15-6-7-16-22-11-29-24(28,23(16,10-15)19(12)30-13(2)25)20(31-14(3)26)18(22)21(4,5)9-8-17(22)27/h15-20,27-28H,1,6-11H2,2-5H3/t15-,16-,17-,18+,19-,20+,22+,23-,24-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Trichokaurin

The herbs of Isodon rubescens

Protocol of Trichokaurin

Structure Identification
J Asian Nat Prod Res. 2005 Feb;7(1):31-6.

Ent-kauranoids from Isodon rubescens var. taihangensis.[Pubmed: 15621599]


METHODS AND RESULTS:
Two new compounds, rubescensins Q and R (1 and 2), and a new acetonide derivative (3) of lasiodonin, together with thirteen known analogues, oridonin (4), ponicidin (5), wikstroemioidin B (6), lasiodonin (7), lasiokaurin (8), enmenol (9), 1-O-beta-D-glucopyranosyl-enmenol (10), Trichokaurin (11), the acetonide of maoyecrystal F (12), rabdoternins A-D (13-16), have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis.
CONCLUSIONS:
Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.

Trichokaurin Dilution Calculator

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Trichokaurin Molarity Calculator

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Preparing Stock Solutions of Trichokaurin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3015 mL 11.5075 mL 23.015 mL 46.0299 mL 57.5374 mL
5 mM 0.4603 mL 2.3015 mL 4.603 mL 9.206 mL 11.5075 mL
10 mM 0.2301 mL 1.1507 mL 2.3015 mL 4.603 mL 5.7537 mL
50 mM 0.046 mL 0.2301 mL 0.4603 mL 0.9206 mL 1.1507 mL
100 mM 0.023 mL 0.1151 mL 0.2301 mL 0.4603 mL 0.5754 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Trichokaurin

Ent-kauranoids from Isodon rubescens var. taihangensis.[Pubmed:15621599]

J Asian Nat Prod Res. 2005 Feb;7(1):31-6.

Two new compounds, rubescensins Q and R (1 and 2), and a new acetonide derivative (3) of lasiodonin, together with thirteen known analogues, oridonin (4), ponicidin (5), wikstroemioidin B (6), lasiodonin (7), lasiokaurin (8), enmenol (9), 1-O-beta-D-glucopyranosyl-enmenol (10), Trichokaurin (11), the acetonide of maoyecrystal F (12), rabdoternins A-D (13-16), have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.

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