(Z)-3-Hydroxy-5-methoxystilbeneCAS# 143207-76-5 |
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| Cas No. | 143207-76-5 | SDF | Download SDF |
| PubChem ID | 14018800 | Appearance | Oil |
| Formula | C15H14O2 | M.Wt | 226.3 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3-methoxy-5-[(Z)-2-phenylethenyl]phenol | ||
| SMILES | COC1=CC(=CC(=C1)O)C=CC2=CC=CC=C2 | ||
| Standard InChIKey | JVIXPWIEOVZVJC-FPLPWBNLSA-N | ||
| Standard InChI | InChI=1S/C15H14O2/c1-17-15-10-13(9-14(16)11-15)8-7-12-5-3-2-4-6-12/h2-11,16H,1H3/b8-7- | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The aerial parts of Polygonum glabrum.
| Description | 1. 3-Hydroxy-5-methoxystilbene exhibits in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 3.33 ug/mL in dormant phase and 3.33 ug/mL in active phase. |
| Targets | Antifection |
(Z)-3-Hydroxy-5-methoxystilbene Dilution Calculator
(Z)-3-Hydroxy-5-methoxystilbene Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.4189 mL | 22.0946 mL | 44.1891 mL | 88.3783 mL | 110.4728 mL |
| 5 mM | 0.8838 mL | 4.4189 mL | 8.8378 mL | 17.6757 mL | 22.0946 mL |
| 10 mM | 0.4419 mL | 2.2095 mL | 4.4189 mL | 8.8378 mL | 11.0473 mL |
| 50 mM | 0.0884 mL | 0.4419 mL | 0.8838 mL | 1.7676 mL | 2.2095 mL |
| 100 mM | 0.0442 mL | 0.2209 mL | 0.4419 mL | 0.8838 mL | 1.1047 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new butenolide cinnamate and other biological active chemical constituents from Polygonum glabrum.[Pubmed:25643642]
Nat Prod Res. 2015;29(22):2080-6.
Phytochemical investigation of the methanol extract of the aerial parts of Polygonum glabrum afforded one new natural product (-)-2-methoxy-2-butenolide-3-cinnamate (1) along with six known compounds, beta-hydroxyfriedalanol (2), 3-hydroxy-5-methoxystilbene (3), (-) pinocembrin (4), sitosterol-(6'-O-palmitoyl)-3-O-beta-D-glucopyranoside (5), (-) pinocembrin-5-methyl ether (6) and sitosterol-3-O-beta-D-glucopyranoside (7). Compound 1 showed promising in vitro anti-HIV-1 activity against primary isolates HIV-1(UG070) (X4, subtype D) and HIV-1(VB59) (R5, subtype C) assayed using TZM-bl cell line with IC50 in the range of 15.68-22.43 mug/mL. The extract showed TI in the range of 19.19-27.37 with IC50 in the range of 10.90-15.55 mug/mL. Compounds 1, 3 and 4 exhibited in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 1.43, 3.33 and 1.11 mug/mL in dormant phase and 2.27, 3.33 and 1.21 mug/mL in active phase, respectively. Compound 4 was found to be the most active antiproliferative with IC50 values of 1.88-11.00 mug/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines.
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