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(Z)-3-Hydroxy-5-methoxystilbene

CAS# 143207-76-5

(Z)-3-Hydroxy-5-methoxystilbene

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Product Name & Size Price Stock
(Z)-3-Hydroxy-5-methoxystilbene: 5mg Please Inquire In Stock
(Z)-3-Hydroxy-5-methoxystilbene: 10mg Please Inquire In Stock
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(Z)-3-Hydroxy-5-methoxystilbene: 200mg Please Inquire Please Inquire
(Z)-3-Hydroxy-5-methoxystilbene: 500mg Please Inquire Please Inquire
(Z)-3-Hydroxy-5-methoxystilbene: 1000mg Please Inquire Please Inquire
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Quality Control of (Z)-3-Hydroxy-5-methoxystilbene

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Chemical structure

(Z)-3-Hydroxy-5-methoxystilbene

3D structure

Chemical Properties of (Z)-3-Hydroxy-5-methoxystilbene

Cas No. 143207-76-5 SDF Download SDF
PubChem ID 14018800 Appearance Oil
Formula C15H14O2 M.Wt 226.3
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-methoxy-5-[(Z)-2-phenylethenyl]phenol
SMILES COC1=CC(=CC(=C1)O)C=CC2=CC=CC=C2
Standard InChIKey JVIXPWIEOVZVJC-FPLPWBNLSA-N
Standard InChI InChI=1S/C15H14O2/c1-17-15-10-13(9-14(16)11-15)8-7-12-5-3-2-4-6-12/h2-11,16H,1H3/b8-7-
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of (Z)-3-Hydroxy-5-methoxystilbene

The aerial parts of Polygonum glabrum.

Biological Activity of (Z)-3-Hydroxy-5-methoxystilbene

Description1. 3-Hydroxy-5-methoxystilbene exhibits in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 3.33 ug/mL in dormant phase and 3.33 ug/mL in active phase.
TargetsAntifection

(Z)-3-Hydroxy-5-methoxystilbene Dilution Calculator

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(Z)-3-Hydroxy-5-methoxystilbene Molarity Calculator

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Preparing Stock Solutions of (Z)-3-Hydroxy-5-methoxystilbene

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4189 mL 22.0946 mL 44.1891 mL 88.3783 mL 110.4728 mL
5 mM 0.8838 mL 4.4189 mL 8.8378 mL 17.6757 mL 22.0946 mL
10 mM 0.4419 mL 2.2095 mL 4.4189 mL 8.8378 mL 11.0473 mL
50 mM 0.0884 mL 0.4419 mL 0.8838 mL 1.7676 mL 2.2095 mL
100 mM 0.0442 mL 0.2209 mL 0.4419 mL 0.8838 mL 1.1047 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on (Z)-3-Hydroxy-5-methoxystilbene

A new butenolide cinnamate and other biological active chemical constituents from Polygonum glabrum.[Pubmed:25643642]

Nat Prod Res. 2015;29(22):2080-6.

Phytochemical investigation of the methanol extract of the aerial parts of Polygonum glabrum afforded one new natural product (-)-2-methoxy-2-butenolide-3-cinnamate (1) along with six known compounds, beta-hydroxyfriedalanol (2), 3-hydroxy-5-methoxystilbene (3), (-) pinocembrin (4), sitosterol-(6'-O-palmitoyl)-3-O-beta-D-glucopyranoside (5), (-) pinocembrin-5-methyl ether (6) and sitosterol-3-O-beta-D-glucopyranoside (7). Compound 1 showed promising in vitro anti-HIV-1 activity against primary isolates HIV-1(UG070) (X4, subtype D) and HIV-1(VB59) (R5, subtype C) assayed using TZM-bl cell line with IC50 in the range of 15.68-22.43 mug/mL. The extract showed TI in the range of 19.19-27.37 with IC50 in the range of 10.90-15.55 mug/mL. Compounds 1, 3 and 4 exhibited in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 1.43, 3.33 and 1.11 mug/mL in dormant phase and 2.27, 3.33 and 1.21 mug/mL in active phase, respectively. Compound 4 was found to be the most active antiproliferative with IC50 values of 1.88-11.00 mug/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines.

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