alpha-Amyrin palmitateCAS# 22255-10-3 |
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| Cas No. | 22255-10-3 | SDF | Download SDF |
| PubChem ID | 185477 | Appearance | Powder |
| Formula | C46H80O2 | M.Wt | 665.1 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(3S,6aR,6bS,8aR,11R,12S,12aS,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-octamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-yl] hexadecanoate | ||
| SMILES | CCCCCCCCCCCCCCCC(=O)OC1CCC2(C(C1(C)C)CCC3(C2CC=C4C3(CCC5(C4C(C(CC5)C)C)C)C)C)C | ||
| Standard InChIKey | BHPGRVQWTLDDQX-MYFXNNOVSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Ficus tikoua
| Description | 1. alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. 2. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin (Ki=6 microM). 3. alpha Amyrin palmitate shows weak cytotoxicity against the A2780 human ovarian cancer cell line. |
| Targets | PKA |
alpha-Amyrin palmitate Dilution Calculator
alpha-Amyrin palmitate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.5035 mL | 7.5177 mL | 15.0353 mL | 30.0707 mL | 37.5883 mL |
| 5 mM | 0.3007 mL | 1.5035 mL | 3.0071 mL | 6.0141 mL | 7.5177 mL |
| 10 mM | 0.1504 mL | 0.7518 mL | 1.5035 mL | 3.0071 mL | 3.7588 mL |
| 50 mM | 0.0301 mL | 0.1504 mL | 0.3007 mL | 0.6014 mL | 0.7518 mL |
| 100 mM | 0.015 mL | 0.0752 mL | 0.1504 mL | 0.3007 mL | 0.3759 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effect of alpha-amyrin palmitate on adjuvant arthritis.[Pubmed:7924889]
Drugs Exp Clin Res. 1994;20(1):1-5.
alpha-Amyrin palmitate was synthesized and tested on adult male Wistar rats made arthritic by subplantar injection of complete Freund's adjuvant. When administered orally at 66 mg/kg BW every 48 h for 5 days from days 32 to 40 post-adjuvant and assessed on day 50, alpha-Amyrin palmitate returned the increases in serum hyaluronate and blood granulocytes toward non-arthritic levels and corrected the moderate anaemia of adjuvant arthritis. Histological examinations of the second and third proximal foot interphalangeal joints showed reduced synovial proliferation and invasion of joints and reduced leucocyte infiltration of bone marrow in alpha-Amyrin palmitate-treated rats. In addition, the drug prevented or reduced bone (subchondral or cortical) and cartilage (articular) destruction in arthritic rats. The results suggest that alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats.
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