Endocrinology Research

Endocrinology is the study of hormones, their signaling pathways, and the diseases associated with them. The endocrine system is one of two mechanisms in the human body that is responsible for regulating and integrating the function of cells, the other being the nervous system.

Endocrinology Research Products Areas

Others (280)

Products for Endocrinology Research - Page 6

Cat.No. Product Name Information/Activity
BCC7062 PPT Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).
BCC7669 WAY 200070 WAY-200070 is a selective estrogen receptor β (ERRβ) agonist with an IC50 of 2.3 nM.
BCC1081 Fulvestrant Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and apoptosis and has antitumor efficacy.
BCC7225 MPP dihydrochloride MPP dihydrochloride is a highly selective estrogen receptor alpha (ERα) antagonist. MPP dihydrochloride reduces the ratio of p-ERα/ERα.
BCC7447 PHTPP PHTPP is a selective ERβ antagonist.
BCC5121 XCT790 XCT-790 is a potent and selective inverse agonist for ERRα with an IC50 value of 0.37 μM. XCT-790 induces cell death in chemotherapeutic resistant cancer cells. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ.
BCC7272 ZK 164015 177583-70-9
BCC1412 Bazedoxifene acetate Bazedoxifene acetate (TSE-424 acetate) is a third generation selective estrogen receptor modulator (SERM) with IC50s of 26 and 99 nM for ERα and ERβ, respectively.
BCC7839 Cyclofenil Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50
BCC6015 (Z)-4-Hydroxytamoxifen 4-Hydroxytamoxifen is a selective estrogen receptor modulator (SERM).