Immune Cell Signaling
Immune cells are functionally regulated by key signaling pathways, which mediate immune function by enabling a response to various stimuli. This response must be carefully moderated in order to avoid hyperresponsiveness or inadequacy in the presence of foreign antigens.
Immune Cell Signaling Products Targets
Products for Immune Cell Signaling - Page 10
- Cat.No. Product Name Information/Activity
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BCC3669
FR 180204
FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC50s of 0.51 μM (Ki=0.31 μM) and 0.33 μM (Ki=0.14 μM), respectively.
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BCC2051
VX-11e
VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK with Ki < 2 nM.
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BCC7745
TMCB
905105-89-7
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BCC2062
XMD8-92
XMD8-92 is a highly selective ERK5/BMK1 inhibitor with dissociation constant (Kd) value of 80 nM.
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BCC6521
DEL-22379
DEL-22379 is an ERK dimerization Inhibitor. DEL-22379 readily binds to ERK2 with a Kd estimated in the low micromolar range, though binding is detectable even at low nanomolar concentrations. ERK2 dimerization is progressively inhibited with an IC50 of ~0.5 μM.
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BCC8088
AEG 3482
63735-71-7
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BCC8089
BI 78D3
BI-78D3 functions as a substrate competitive inhibitor of JNK, inhibit the JNK kinase activity (IC50=280 nM).
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BCC7982
CEP 1347
156177-65-0
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BCC8085
c-JUN peptide
610273-01-3
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BCC8093
IQ 3
312538-03-7
