Addiction Research
According to the World Health Organization (WHO), addiction is 'a chronic disease of the central nervous system that is characterized by a loss of control over impulsive behavior that leads to compulsive drug seeking and taking, and to relapses even after months of abstinence'. Addiction is a complex neuroadaptive process, where drugs of abuse alter cellular and molecular aspects of neural function. The brain circuits mediating the various behavioral effects of these drugs are rendered more, or less, responsive to those effects.
Addiction Research Products Targets
- Others (13)
- D4 Receptor (12)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- NOP Receptor (21)
- Mu-Opioid Receptors (15)
- Kappa Opioid Receptors (14)
- AMPA Receptor (45)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- Nicotinic (α7) Receptor (25)
- Nicotinic (α4β2) Receptor (14)
- D3 Receptor (12)
- NMDA Receptor (87)
- Kainate Receptor (22)
- D2 Receptor (14)
- D1 and D5 Receptor (16)
- Glutamate Transporter (18)
- Dopamine Transporter (20)
- CRF2 Receptor (3)
- CRF1 Receptor (5)
- 5-HT Transporter (30)
- Delta opioid receptor (16)
Products for Addiction Research - Page 11
- Cat.No. Product Name Information/Activity
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BCC6681
8-Hydroxy-DPAT hydrobromide
76135-31-4
-
BCC6266
LP 20 hydrochloride
1386928-34-2
-
BCC7705
3-Bromocytisine
3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively.
-
BCC7099
5-Iodo-A-85380 dihydrochloride
1217837-17-6
-
BCC7102
5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative
213766-21-3
-
BCC3821
Nicotine Difartrate
65-31-6
-
BCC6118
3-pyr-Cytisine
948027-43-8
-
BCC1902
RJR-2403 oxalate
Rivanicline oxalate (RJR-2403 oxalate; (E)-Metanicotine oxalate) is a neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki=26 nM); > 1,000 fold selectivity than α7 receptors(Ki= 3.6 μM).
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BCC7975
SIB 1508Y maleate
192231-16-6
-
BCC7469
TC 2559 difumarate
212332-35-9


