Addiction Research

According to the World Health Organization (WHO), addiction is 'a chronic disease of the central nervous system that is characterized by a loss of control over impulsive behavior that leads to compulsive drug seeking and taking, and to relapses even after months of abstinence'. Addiction is a complex neuroadaptive process, where drugs of abuse alter cellular and molecular aspects of neural function. The brain circuits mediating the various behavioral effects of these drugs are rendered more, or less, responsive to those effects.

Addiction Research Products Targets

Products for Addiction Research - Page 11

  1. Cat.No. Product Name Information/Activity
  2. BCC6681 8-Hydroxy-DPAT hydrobromide 76135-31-4 8-Hydroxy-DPAT hydrobromide chemical structure
  3. BCC6266 LP 20 hydrochloride 1386928-34-2 LP 20 hydrochloride chemical structure
  4. BCC7705 3-Bromocytisine 3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively. 3-Bromocytisine chemical structure
  5. BCC7099 5-Iodo-A-85380 dihydrochloride 1217837-17-6 5-Iodo-A-85380 dihydrochloride chemical structure
  6. BCC7102 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative 213766-21-3 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative chemical structure
  7. BCC3821 Nicotine Difartrate 65-31-6 Nicotine Difartrate chemical structure
  8. BCC6118 3-pyr-Cytisine 948027-43-8 3-pyr-Cytisine chemical structure
  9. BCC1902 RJR-2403 oxalate Rivanicline oxalate (RJR-2403 oxalate; (E)-Metanicotine oxalate) is a neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki=26 nM); > 1,000 fold selectivity than α7 receptors(Ki= 3.6 μM). RJR-2403 oxalate chemical structure
  10. BCC7975 SIB 1508Y maleate 192231-16-6 SIB 1508Y maleate chemical structure
  11. BCC7469 TC 2559 difumarate 212332-35-9 TC 2559 difumarate chemical structure

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