Addiction Research

According to the World Health Organization (WHO), addiction is 'a chronic disease of the central nervous system that is characterized by a loss of control over impulsive behavior that leads to compulsive drug seeking and taking, and to relapses even after months of abstinence'. Addiction is a complex neuroadaptive process, where drugs of abuse alter cellular and molecular aspects of neural function. The brain circuits mediating the various behavioral effects of these drugs are rendered more, or less, responsive to those effects.

Addiction Research Products Targets

Products for Addiction Research - Page 4

Cat.No. Product Name Information/Activity
BCC6846 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride 202646-03-5
BCC6753 BTCP maleate 207455-25-2
BCC6845 3-CPMT 14008-79-8
BCC6676 GBR 12783 dihydrochloride GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively. GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.
BCC5129 Vanoxerine dihydrochloride Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) binds to the target site on the dopamine transporter (DAT).
BCC5380 GBR 12935 dihydrochloride GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor.
BCC6640 GBR 13069 dihydrochloride 67469-45-8
BCC7923 JHW 007 hydrochloride 202645-74-7
BCC5818 Threo-methylphenidate hydrochloride 298-59-9
BCC7226 Nomifensine Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.