Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 35

  1. Cat.No. Product Name Information/Activity
  2. BCC7475 L-748,337 244192-94-7 L-748,337 chemical structure
  3. BCC7094 SR 59230A hydrochloride SR59230A hydrochloride is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively. SR 59230A hydrochloride chemical structure
  4. BCC6978 2-APB 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). 2-APB chemical structure
  5. BCC7002 (-)-Xestospongin C 88903-69-9 (-)-Xestospongin C chemical structure
  6. BCN5807 Caffeine 58-08-2 Caffeine chemical structure
  7. BCC7808 NAADP tetrasodium salt 5502-96-5 NAADP tetrasodium salt chemical structure
  8. BCC7079 Suramin hexasodium salt Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM). Suramin sodium salt is an antitrypanosomal, anti-neoplastic and anti-angiogenic agent. Suramin hexasodium salt chemical structure
  9. BCC6673 Dantrolene, sodium salt 14663-23-1 Dantrolene, sodium salt chemical structure
  10. BCC7067 Ruthenium Red 11103-72-3 Ruthenium Red chemical structure
  11. BCC5742 Ryanodine Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Ryanodine chemical structure

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