Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 28

  1. Cat.No. Product Name Information/Activity
  2. BCC2494 Alfuzosin HCl Alfuzosin hydrochloride is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH). Alfuzosin HCl chemical structure
  3. BCC5063 BMY 7378 5-HT<sub>1A</sub> partial agonist,BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3. BMY 7378 chemical structure
  4. BCC4324 Carvedilol Carvedilol (BM 14190) is a non-selective β/α-1 blocker. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome. Carvedilol chemical structure
  5. BCC1257 Doxazosin Mesylate Doxazosin mesylate (UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. Doxazosin Mesylate chemical structure
  6. BCC6683 HEAT hydrochloride 30007-39-7 HEAT hydrochloride chemical structure
  7. BCC6688 Ifenprodil hemitartrate 23210-56-2 Ifenprodil hemitartrate chemical structure
  8. BCC6741 2-MPMDQ 149847-77-8 2-MPMDQ chemical structure
  9. BCC6947 (S)-(+)-Niguldipine hydrochloride 113145-69-0 (S)-(+)-Niguldipine hydrochloride chemical structure
  10. BCC6726 2-PMDQ 139047-55-5 2-PMDQ chemical structure
  11. BCC2505 Prazosin HCl Prazosin hydrochloride is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder. Prazosin HCl chemical structure

Items 271 to 280 of 752 total