Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 27

  1. Cat.No. Product Name Information/Activity
  2. BCC6106 MRE 3008F20 MRE3008F20 is a highly potent and selective antagonist of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM. MRE 3008F20 chemical structure
  3. BCC6972 MRS 1220 183721-15-5 MRS 1220 chemical structure
  4. BCC5753 MRS 1334 192053-05-7 MRS 1334 chemical structure
  5. BCC7238 PSB 10 hydrochloride 591771-91-4 PSB 10 hydrochloride chemical structure
  6. BCC7239 PSB 11 hydrochloride 453591-58-7 PSB 11 hydrochloride chemical structure
  7. BCC7030 VUF 5574 280570-45-8 VUF 5574 chemical structure
  8. BCC6912 A 61603 hydrobromide 107756-30-9 A 61603 hydrobromide chemical structure
  9. BCC6833 Cirazoline hydrochloride Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM). Cirazoline hydrochloride chemical structure
  10. BCC4333 Oxymetazoline HCl 2315-02-8 Oxymetazoline HCl chemical structure
  11. BCC4335 Phenylephrine HCl (R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively. Phenylephrine HCl chemical structure

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