Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 58

  1. Cat.No. Product Name Information/Activity
  2. BCC4590 NMDA (N-Methyl-D-aspartic acid) NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. NMDA (N-Methyl-D-aspartic acid) chemical structure
  3. BCC6573 Quinolinic acid Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction. Quinolinic acid chemical structure
  4. BCC6865 Spermidine trihydrochloride Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents. Spermidine trihydrochloride chemical structure
  5. BCC6599 (RS)-(Tetrazol-5-yl)glycine (RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is a highly potent and selective N-methyl-D-aspartate (NMDA) receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D and GluN1/GluN2A, respectively. (RS)-(Tetrazol-5-yl)glycine induces seizure responses and Fos in mice. (RS)-(Tetrazol-5-yl)glycine chemical structure
  6. BCC6584 ACBC 22264-50-2 ACBC chemical structure
  7. BCC7753 DL-AP5 Sodium salt 1303993-72-7 DL-AP5 Sodium salt chemical structure
  8. BCC6553 D-AP5 D-AP5 is a NMDA receptor antagonist. D-AP5 chemical structure
  9. BCC6552 DL-AP5 76326-31-3 DL-AP5 chemical structure
  10. BCC6554 L-AP5 79055-67-7 L-AP5 chemical structure
  11. BCC6551 DL-AP7 78966-69-5 DL-AP7 chemical structure

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