Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 61

  1. Cat.No. Product Name Information/Activity
  2. BCC7280 Eliprodil Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). Eliprodil chemical structure
  3. BCC4904 Felbamate Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA). Felbamate chemical structure
  4. BCC7340 Gavestinel 153436-38-5 Gavestinel chemical structure
  5. BCC6589 (S)-(-)-HA-966 111821-58-0 (S)-(-)-HA-966 chemical structure
  6. BCC5946 HU 211 Dexanabinol (HU-211) is an artificially synthesized cannabinoid derivative and lacks cannabimimetic effects. Dexanabinol exhibits not only the antioxidant and neuroprotective activities in brain but also anti-inflammatory activity by inhibiting NF-κB and decreasing cytokines such as TNFα and interleukin-6, which could ensure the integrity of BBB and reduce cell apoptosis and death. Dexanabinol is widely used in head injury or stroke treatment and has been shown to be safe in animals and humans. HU 211 chemical structure
  7. BCC6594 N-(4-Hydroxyphenylacetyl)spermine 130210-32-1 N-(4-Hydroxyphenylacetyl)spermine chemical structure
  8. BCC7508 threo Ifenprodil hemitartrate 1312991-83-5 threo Ifenprodil hemitartrate chemical structure
  9. BCC5982 Ketamine hydrochloride 1867-66-9 Ketamine hydrochloride chemical structure
  10. BCC7930 (S)-(+)-Ketamine hydrochloride 33643-47-9 (S)-(+)-Ketamine hydrochloride chemical structure
  11. BCC6774 L-689,560 L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases. L-689,560 chemical structure

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