Stress and Anxiety Research

Stress is a valuable evolutionary-conserved physiological response to threatening or adverse environments. Chronic stress is a pathological state that is caused by prolonged upregulation of the normal acute stress response. Anxiety disorders, such as phobias and post-traumatic stress disorder, are due to fear conditioning to a neutral stimulus and involve many of the same brain regions as stress.

Stress and Anxiety Research Products Targets

Products for Stress and Anxiety Research - Page 4

Cat.No. Product Name Information/Activity
BCC6709 Metergoline Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors.
BCC5663 2-Methyl-5-hydroxytryptamine hydrochloride 2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects.
BCC1114 Mianserin HCl Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.
BCC7218 AS 19 AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia.
BCC7517 LP 12 hydrochloride 1185136-22-4
BCC7399 LP 44 824958-12-5
BCC7990 DR 4485 hydrochloride 402942-53-4
BCC7101 LY 215840 137328-52-0
BCC5937 SB 258719 hydrochloride 1217674-10-6
BCC5056 SB269970 HCl SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors.