Respiratory Disease Research

The respiratory system consists of the lungs, airways, diaphragm, trachea (windpipe) and pharynx (throat) and its primary function is the exchange of oxygen and carbon dioxide- breathing in and out. Between 6 and 10 liters of air are brought in and out of the lungs and 0.3 liters of oxygen are transferred from the alveoli to the blood per minute.

Respiratory Disease Research Products Areas

Products for Respiratory Disease Research - Page 14

  1. Cat.No. Product Name Information/Activity
  2. BCC7598 PSB 603 1092351-10-4 PSB 603 chemical structure
  3. BCC6313 Eact Eact is a selective and potent activator of TMEM16A, directly activates the TRPV1 channels in sensory nociceptors and produces itch, acute nociception and thermal hypersensitivity. Eact chemical structure
  4. BCC4634 Benzbromarone Benzbromarone is a highly effective and well tolerated non-competitive inhibitor of xanthine oxidase, used as an uricosuric agent, used in the treatment of gout. Benzbromarone chemical structure
  5. BCC6314 CaCCinh-A01 CaCCinh-A01 is an inhibitor of both TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM, respectively. CaCCinh-A01 chemical structure
  6. BCC4419 CFTRinh-172 CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel; reversibly inhibits CFTR short-circuit current in less than 2 minutes with a Ki of 300 nM. CFTRinh-172 chemical structure
  7. BCC7055 Chromanol 293B 163163-23-3 Chromanol 293B chemical structure
  8. BCC7105 DCPIB DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 (IC50s, 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM in CPAE cells. DCPIB chemical structure
  9. BCC7942 DIDS Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor DIDS chemical structure
  10. BCC6326 GaTx2 194665-85-5 GaTx2 chemical structure
  11. BCC4784 Glyburide Glibenclamide is a selective inhibitor of ATP-sensitive K+ channel. Glyburide chemical structure

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