Respiratory Disease Research

The respiratory system consists of the lungs, airways, diaphragm, trachea (windpipe) and pharynx (throat) and its primary function is the exchange of oxygen and carbon dioxide- breathing in and out. Between 6 and 10 liters of air are brought in and out of the lungs and 0.3 liters of oxygen are transferred from the alveoli to the blood per minute.

Respiratory Disease Research Products Areas

Products for Respiratory Disease Research - Page 21

Cat.No. Product Name Information/Activity
BCC3878 LY335979 (Zosuquidar 3HCL) Zosuquidar trihydrochloride is an inhibitor of P-glycoprotein with a Ki value of 59 nM.
BCN2961 Ingenol 3-Angelate Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
BCC8082 cAMPS-Rp, triethylammonium salt Rp-cAMPS triethylammonium salt is an analog of cAMP which acts as a potent, competitive and cell-permeable antagonist of cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 6.05 µM and 9.75 µM, respectively). Rp-cAMPS triethylammonium salt is resistant to hydrolysis by phosphodiesterases.
BCC2542 Fasudil (HA-1077) HCl Fasudil Hydrochloride (HA-1077 Hydrochloride; AT877 Hydrochloride), is a nonspecific ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator.
BCC8084 cGMP Dependent Kinase Inhibitor Peptide 82801-73-8
BCC4997 H 89 2HCl H-89 dihydrochloride is a potent and selective inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase.
BCC8080 KT 5720 KT5720 is a cell-permeable, potent, specific, reversible, ATP-competitive inhibitor of protein kinase A (PKA), with a Ki of 60 nM.
BCC1042 PKA inhibitor fragment (6-22) amide Potent protein kinase A inhibitor
BCC8087 PKI 14-22 amide, myristoylated Cell-permeable protein kinase A inhibitor
BCC8081 cAMPS-Sp, triethylammonium salt 93602-66-5