Products for Phospholipase
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BCC7715
VU 0155069
VU0155069 (CAY10593), compound 69, is a selective phospholipase D1 (PLD1) inhibitor with an IC50 value of 46 nM in vitro. VU0155069 (CAY10593) strongly inhibits the invasive migration of several cancer cell lines in transwell assays.
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BCC4178
CAY10650
CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC 50 value of 12 nM.
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BCC7875
VU 0364739 hydrochloride
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BCC4179
GSK 2830371
GSK 2830371 is a highly selective Wip1 phosphatase inhibitor with IC50 of 6 nM.
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BCC7074
PACOCF3
Phospholipase A<sub>2</sub> inhibitor
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BCC7396
YM 26734
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BCC7075
AACOCF3
Phospholipase A<sub>2</sub> inhibitor
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BCC5610
JJKK 048
JJKK 048 is an ultrapotent and highly selective inhibitor of Monoacylglycerol lipase (MAGL).
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BCC7728
LY 311727
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BCC2310
Varespladib (LY315920)
Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.
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BCC3757
CP-91149
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
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BCC6039
CP 316819
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BCC7209
m-3M3FBS
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BCC6716
OBAA
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BCC7210
o-3M3FBS
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BCC7537
Edelfosine
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BCC5612
ML 349
ML349 is a potent and specific acyl protein thioesterase 2 (APT-2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM.
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BCC5611
ML 348
ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2.
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BCC6091
GPi 688
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BCC7721
FIPI
FIPI is a derivative of halopemide which potently inhibits both PLD1 and PLD2 with IC50s of 25 nM and 20 nM, respectively.
