VU 0364739 hydrochloridePotent and selective PLD2 inhibitor CAS# 1244640-48-9 |
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Quality Control & MSDS
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| Cas No. | 1244640-48-9 | SDF | Download SDF |
| PubChem ID | 46939225 | Appearance | Powder |
| Formula | C26H28ClFN4O2 | M.Wt | 482.98 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 100 mM in DMSO | ||
| Chemical Name | N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide;hydrochloride | ||
| SMILES | C1CN(CCC12C(=O)NCN2C3=CC(=CC=C3)F)CCNC(=O)C4=CC5=CC=CC=C5C=C4.Cl | ||
| Standard InChIKey | RYLAMDMOILNBKN-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C26H27FN4O2.ClH/c27-22-6-3-7-23(17-22)31-18-29-25(33)26(31)10-13-30(14-11-26)15-12-28-24(32)21-9-8-19-4-1-2-5-20(19)16-21;/h1-9,16-17H,10-15,18H2,(H,28,32)(H,29,33);1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Potent and selective phospholipase D2 (PLD2) inhibitor (IC50 = 20 nM); displays 75-fold selectivity against PLD1 (IC50 = 1500 nM). |
VU 0364739 hydrochloride Dilution Calculator
VU 0364739 hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0705 mL | 10.3524 mL | 20.7048 mL | 41.4096 mL | 51.762 mL |
| 5 mM | 0.4141 mL | 2.0705 mL | 4.141 mL | 8.2819 mL | 10.3524 mL |
| 10 mM | 0.207 mL | 1.0352 mL | 2.0705 mL | 4.141 mL | 5.1762 mL |
| 50 mM | 0.0414 mL | 0.207 mL | 0.4141 mL | 0.8282 mL | 1.0352 mL |
| 100 mM | 0.0207 mL | 0.1035 mL | 0.207 mL | 0.4141 mL | 0.5176 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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