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VU 0364739 hydrochloride

Potent and selective PLD2 inhibitor CAS# 1244640-48-9

VU 0364739 hydrochloride

Catalog No. BCC7875----Order now to get a substantial discount!

Product Name & Size Price Stock
VU 0364739 hydrochloride: 5mg $138 In Stock
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Chemical structure

VU 0364739 hydrochloride

3D structure

Chemical Properties of VU 0364739 hydrochloride

Cas No. 1244640-48-9 SDF Download SDF
PubChem ID 46939225 Appearance Powder
Formula C26H28ClFN4O2 M.Wt 482.98
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble to 100 mM in DMSO
Chemical Name N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide;hydrochloride
SMILES C1CN(CCC12C(=O)NCN2C3=CC(=CC=C3)F)CCNC(=O)C4=CC5=CC=CC=C5C=C4.Cl
Standard InChIKey RYLAMDMOILNBKN-UHFFFAOYSA-N
Standard InChI InChI=1S/C26H27FN4O2.ClH/c27-22-6-3-7-23(17-22)31-18-29-25(33)26(31)10-13-30(14-11-26)15-12-28-24(32)21-9-8-19-4-1-2-5-20(19)16-21;/h1-9,16-17H,10-15,18H2,(H,28,32)(H,29,33);1H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of VU 0364739 hydrochloride

DescriptionPotent and selective phospholipase D2 (PLD2) inhibitor (IC50 = 20 nM); displays 75-fold selectivity against PLD1 (IC50 = 1500 nM).

VU 0364739 hydrochloride Dilution Calculator

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VU 0364739 hydrochloride Molarity Calculator

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Preparing Stock Solutions of VU 0364739 hydrochloride

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0705 mL 10.3524 mL 20.7048 mL 41.4096 mL 51.762 mL
5 mM 0.4141 mL 2.0705 mL 4.141 mL 8.2819 mL 10.3524 mL
10 mM 0.207 mL 1.0352 mL 2.0705 mL 4.141 mL 5.1762 mL
50 mM 0.0414 mL 0.207 mL 0.4141 mL 0.8282 mL 1.0352 mL
100 mM 0.0207 mL 0.1035 mL 0.207 mL 0.4141 mL 0.5176 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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