Laxiracemosin HCAS# 1241871-28-2 |
Quality Control & MSDS
3D structure
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| Cas No. | 1241871-28-2 | SDF | Download SDF |
| PubChem ID | 46918651 | Appearance | Powder |
| Formula | C26H35NO3 | M.Wt | 409.57 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3-[(5R,9R,10R,13S,14S,17R)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]pyrrole-2,5-dione | ||
| SMILES | CC1(C2CC=C3C(C2(CCC1=O)C)CCC4(C3(CCC4C5=CC(=O)NC5=O)C)C)C | ||
| Standard InChIKey | MBOKEBRRTSUMOO-CVRFEKSNSA-N | ||
| Standard InChI | InChI=1S/C26H35NO3/c1-23(2)19-7-6-18-17(24(19,3)11-10-20(23)28)9-13-25(4)16(8-12-26(18,25)5)15-14-21(29)27-22(15)30/h6,14,16-17,19H,7-13H2,1-5H3,(H,27,29,30)/t16-,17-,19-,24+,25-,26+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Laxiracemosin H is a natural product from Dysoxylum lenticellatum. |
| In vitro | Chemical constituents from Dysoxylum lenticellatum.[Reference: WebLink]Chinese Traditional & Herbal Drugs, 2012, 43(1):38-42.To study the chemical constituents from the stems of Dysoxylum lenticellatum and their cytotoxic activities. |
Laxiracemosin H Dilution Calculator
Laxiracemosin H Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4416 mL | 12.2079 mL | 24.4159 mL | 48.8317 mL | 61.0396 mL |
| 5 mM | 0.4883 mL | 2.4416 mL | 4.8832 mL | 9.7663 mL | 12.2079 mL |
| 10 mM | 0.2442 mL | 1.2208 mL | 2.4416 mL | 4.8832 mL | 6.104 mL |
| 50 mM | 0.0488 mL | 0.2442 mL | 0.4883 mL | 0.9766 mL | 1.2208 mL |
| 100 mM | 0.0244 mL | 0.1221 mL | 0.2442 mL | 0.4883 mL | 0.6104 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Chemical constituents from Dysoxylum lenticellatum.
Chinese Traditional & Herbal Drugs, 2012, 43(1):38-42.
To study the chemical constituents from the stems of Dysoxylum lenticellatum and their cytotoxic activities.Methods Silica gel,RP-18,and Sephadex LH-20 column chromatography techniques were used for separation and purification of the compounds and extensive spectral analysis spectra were employed for structural elucidation.The cytotoxic activity was evaluated by MTT method.Results Twelve compounds were isolated from D.lenticellatum and their structures were identified as β-sitosterol(1),stigmasterol(2),3-oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone(3),3α-hydroxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone(4),Laxiracemosin H(5),laxiracemosin B(6),24,25-epoxy-tirucall-7-ene-3,23-dione(7),butyrospermol(8),oleanolic acid(9),taraxerone(10),taraxerol(11),and 8-hydroxy-6-methoxy-3-pentylisocoumarin(12).Conclusion All of these compounds are isolated from D.lenticellatum for the first time and the compounds 8,10—12 are reported from the plants in Dysoxylum Bl.for the first time.What’s more,compounds 5 and 6 are tirucallane-type alkaloids and compound 3 shows significant inhibitory activities against human cancer cell lines in vitro.
