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(-)-Hydroxydihydrobovolide

CAS# 124097-54-7

(-)-Hydroxydihydrobovolide

Catalog No. BCN7890----Order now to get a substantial discount!

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(-)-Hydroxydihydrobovolide: 5mg Please Inquire In Stock
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Quality Control of (-)-Hydroxydihydrobovolide

Number of papers citing our products

Chemical structure

(-)-Hydroxydihydrobovolide

3D structure

Chemical Properties of (-)-Hydroxydihydrobovolide

Cas No. 124097-54-7 SDF Download SDF
PubChem ID 328789 Appearance Powder
Formula C11H18O3 M.Wt 198.26
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5-hydroxy-3,4-dimethyl-5-pentylfuran-2-one
SMILES CCCCCC1(C(=C(C(=O)O1)C)C)O
Standard InChIKey VJZWZDQDXPADSE-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H18O3/c1-4-5-6-7-11(13)9(3)8(2)10(12)14-11/h13H,4-7H2,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of (-)-Hydroxydihydrobovolide

The herbs of Clausena emarginata Huang

Biological Activity of (-)-Hydroxydihydrobovolide

Description(-)-Hydroxydihydrobovolide is a natural product from Clausena emarginata Huang.
In vitro

Antimalarial compounds from Rhaphidophora decursiva.[Pubmed: 11421741]

J Nat Prod. 2001 Jun;64(6):772-7.


METHODS AND RESULTS:
Bioassay-directed fractionation led to the isolation of 14 compounds, six of which possess antimalarial activity, from the dried leaves and stems of Rhaphidophora decursiva. Polysyphorin (1) and rhaphidecurperoxin (6) showed strong activities against Plasmodium falciparum. Rhaphidecursinol A (2), rhaphidecursinol B (3), grandisin (4), and epigrandisin (5) were less active against the same organism. Among the isolates, rhaphidecursinol A (2) and rhaphidecursinol B (3) were determined to be new neolignans, and rhaphidecurperoxin (6) is a new benzoperoxide.
CONCLUSIONS:
Known compounds isolated include polysyphorin (1), grandisin (4), epigrandisin (5), (+)-medioresinol, (-)-pinoresinol, (-)-syringaresinol, (+)-glaberide I, (+)-dehydrovomifoliol, (-)-liliolide, (-)-Hydroxydihydrobovolide, and N-butylbenzamide, of which compound 1 appears worthy of further evaluation as an antimalarial agent. Structure elucidation and identification were accomplished by spectroscopic means including 1D and 2D NMR analyses.

(-)-Hydroxydihydrobovolide Dilution Calculator

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(-)-Hydroxydihydrobovolide Molarity Calculator

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Preparing Stock Solutions of (-)-Hydroxydihydrobovolide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.0439 mL 25.2194 mL 50.4388 mL 100.8776 mL 126.097 mL
5 mM 1.0088 mL 5.0439 mL 10.0878 mL 20.1755 mL 25.2194 mL
10 mM 0.5044 mL 2.5219 mL 5.0439 mL 10.0878 mL 12.6097 mL
50 mM 0.1009 mL 0.5044 mL 1.0088 mL 2.0176 mL 2.5219 mL
100 mM 0.0504 mL 0.2522 mL 0.5044 mL 1.0088 mL 1.261 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on (-)-Hydroxydihydrobovolide

Antimalarial compounds from Rhaphidophora decursiva.[Pubmed:11421741]

J Nat Prod. 2001 Jun;64(6):772-7.

Bioassay-directed fractionation led to the isolation of 14 compounds, six of which possess antimalarial activity, from the dried leaves and stems of Rhaphidophora decursiva. Polysyphorin (1) and rhaphidecurperoxin (6) showed strong activities against Plasmodium falciparum. Rhaphidecursinol A (2), rhaphidecursinol B (3), grandisin (4), and epigrandisin (5) were less active against the same organism. Among the isolates, rhaphidecursinol A (2) and rhaphidecursinol B (3) were determined to be new neolignans, and rhaphidecurperoxin (6) is a new benzoperoxide. Known compounds isolated include polysyphorin (1), grandisin (4), epigrandisin (5), (+)-medioresinol, (-)-pinoresinol, (-)-syringaresinol, (+)-glaberide I, (+)-dehydrovomifoliol, (-)-liliolide, (-)-Hydroxydihydrobovolide, and N-butylbenzamide, of which compound 1 appears worthy of further evaluation as an antimalarial agent. Structure elucidation and identification were accomplished by spectroscopic means including 1D and 2D NMR analyses.

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