AlcesefolisideCAS# 124151-38-8 |
| Cas No. | 124151-38-8 | SDF | File under preparation. |
| PubChem ID | 11828754 | Appearance | Yellow powder |
| Formula | C33H40O20 | M.Wt | 756.7 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-(3,4-dihydroxyphenyl)-3-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5,7-dihydroxychromen-4-one | ||
| SMILES | CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)OC6C(C(C(C(O6)C)O)O)O)O)O)O)O)O | ||
| Standard InChIKey | HKNBJSRIYRDSLB-MIORVHIISA-N | ||
| Standard InChI | InChI=1S/C33H40O20/c1-9-19(38)23(42)26(45)31(48-9)47-8-17-21(40)25(44)30(53-32-27(46)24(43)20(39)10(2)49-32)33(51-17)52-29-22(41)18-15(37)6-12(34)7-16(18)50-28(29)11-3-4-13(35)14(36)5-11/h3-7,9-10,17,19-21,23-27,30-40,42-46H,8H2,1-2H3/t9-,10-,17+,19-,20-,21-,23+,24+,25-,26+,27+,30+,31+,32-,33-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
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The herbs of Rubus alceaefolius Poir.
| Description | 1. Alcesefoliside has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL. |
Alcesefoliside Dilution Calculator
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| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.3215 mL | 6.6076 mL | 13.2153 mL | 26.4306 mL | 33.0382 mL |
| 5 mM | 0.2643 mL | 1.3215 mL | 2.6431 mL | 5.2861 mL | 6.6076 mL |
| 10 mM | 0.1322 mL | 0.6608 mL | 1.3215 mL | 2.6431 mL | 3.3038 mL |
| 50 mM | 0.0264 mL | 0.1322 mL | 0.2643 mL | 0.5286 mL | 0.6608 mL |
| 100 mM | 0.0132 mL | 0.0661 mL | 0.1322 mL | 0.2643 mL | 0.3304 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Flavoalkaloids and Flavonoids from Astragalus monspessulanus.[Pubmed:26558405]
J Nat Prod. 2015 Nov 25;78(11):2565-71.
A new flavonol tetraglycoside, quercetin-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->6)]- beta-D-galactopyranosyl]-7-O-beta-D-glucopyranoside (1), and two new flavonol alkaloids, N-(8-methylquercetin-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosy l-(1-->6)]-beta-D-galactopyranosyl])-3-hydroxypiperidin-2-one (2) and N-(8-methylkaempferol-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranos yl-(1-->6)]-beta-D-galactopyranosyl])-3-hydroxypiperidin-2-one (3), were isolated from the aerial parts of Astragalus monspessulanus ssp. monspessulanus. Two rare flavonoids with an unusual 3-hydroxy-3-methylglutaric acid moiety, quercetin-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[6-O-(3-hydroxy-3-methylglutaryl)-b eta-D-galactopyranoside (4) and kaempferol-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[6-O-(3-hydroxy-3-methylglutaryl)- beta-D-galactopyranoside (5), were isolated from the aerial parts of A. monspessulanus ssp. illyricus. In addition, the eight known flavonoids alangiflavoside (6), Alcesefoliside (7), mauritianin (8), quercetin-3-beta-robinobioside (9), cosmosine (10), apigenin-4'-O-glucoside (11), trifolin (12), and rutin (13) were isolated from aerial parts of A. monspessulanus ssp. monspessulanus. Their structures were elucidated via NMR and HRESIMS data. In a model that tested t-BuOOH-induced oxidative stress on isolated rat hepatocytes, flavonoids 1-13 had statistically significant cytoprotective activity similar to that of silymarin, tested at 60 mug/mL. The most prominent effects were observed for flavonoids 1, 4, 7, and 12.
Alcesefoliside is a flavonoid isolated from Nitraria sibirica Pall, with antioxidant activity.
Alcesefoliside (CAS 124151-38-8) is a natural product offered by BioCrick for research applications. Customers can buy or order Alcesefoliside from BioCrick, a supplier and manufacturer of research chemicals, with product specifications, purity, packaging, and pricing information available upon request.
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