Quercetin-3-gentiobiosideCAS# 7431-83-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 7431-83-6 | SDF | Download SDF |
PubChem ID | 5320834 | Appearance | Yellow powder |
Formula | C27H30O17 | M.Wt | 626.5 |
Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
Synonyms | 3,3',4',5,7-Pentahydroxyflavone 3-gentiobioside | ||
Solubility | Soluble in acetonitrile | ||
Chemical Name | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one | ||
SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)COC5C(C(C(C(O5)CO)O)O)O)O)O)O)O)O | ||
Standard InChIKey | FDRQPMVGJOQVTL-DEFKTLOSSA-N | ||
Standard InChI | InChI=1S/C27H30O17/c28-6-14-17(33)20(36)22(38)26(42-14)40-7-15-18(34)21(37)23(39)27(43-15)44-25-19(35)16-12(32)4-9(29)5-13(16)41-24(25)8-1-2-10(30)11(31)3-8/h1-5,14-15,17-18,20-23,26-34,36-39H,6-7H2/t14-,15-,17-,18-,20+,21+,22-,23-,26-,27+/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Quercetin-3-gentiobioside may show significant inhibitor on AR and AGEs formation activities. |
In vitro | Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds.[Pubmed: 28512639 ]Biomed Res Int. 2017;2017:7375615.Blocking the polyol pathway plays an important role preventing diabetic complications. Therefore, aldose reductase (AR) and advanced glycation endproducts (AGEs) formation has significant effect on diabetic complications. Artemisia iwayomogi has long been used as treatment of various diseases in Korea. However, no literatures have reported on AR and AGEs formation inhibitory activities of A. iwayomogi.
|
Quercetin-3-gentiobioside Dilution Calculator
Quercetin-3-gentiobioside Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.5962 mL | 7.9808 mL | 15.9617 mL | 31.9234 mL | 39.9042 mL |
5 mM | 0.3192 mL | 1.5962 mL | 3.1923 mL | 6.3847 mL | 7.9808 mL |
10 mM | 0.1596 mL | 0.7981 mL | 1.5962 mL | 3.1923 mL | 3.9904 mL |
50 mM | 0.0319 mL | 0.1596 mL | 0.3192 mL | 0.6385 mL | 0.7981 mL |
100 mM | 0.016 mL | 0.0798 mL | 0.1596 mL | 0.3192 mL | 0.399 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Sinapine thiocyanate
Catalog No.:BCN2765
CAS No.:7431-77-8
- Triptophenolide
Catalog No.:BCN2546
CAS No.:74285-86-2
- 12-Oxograndiflorenic acid
Catalog No.:BCN7624
CAS No.:74284-42-7
- 7-Acetylintermedine
Catalog No.:BCN1998
CAS No.:74243-01-9
- p-Chlorophenylalanine
Catalog No.:BCC5689
CAS No.:7424-00-2
- Baogongteng A
Catalog No.:BCN1874
CAS No.:74239-84-2
- Doronenine
Catalog No.:BCN2066
CAS No.:74217-57-5
- OSU-03012 (AR-12)
Catalog No.:BCC1255
CAS No.:742112-33-0
- Carbenoxolone disodium
Catalog No.:BCC3745
CAS No.:7421-40-1
- Vintafolide
Catalog No.:BCC5265
CAS No.:742092-03-1
- 3-Bromo-7-nitroindazole
Catalog No.:BCC6770
CAS No.:74209-34-0
- Uplandicine
Catalog No.:BCN2055
CAS No.:74202-10-1
- Somatostatin 1-28
Catalog No.:BCC5715
CAS No.:74315-46-1
- Z-Trp-OH
Catalog No.:BCC2750
CAS No.:7432-21-5
- Schisandrin A
Catalog No.:BCN5815
CAS No.:7432-28-2
- 4',4'''-Di-O-methylcupressuflavone
Catalog No.:BCN4295
CAS No.:74336-91-7
- (RS)-AMPA
Catalog No.:BCC6560
CAS No.:74341-63-2
- Chidamide
Catalog No.:BCC6445
CAS No.:743420-02-2
- Ent-16Α,17-Dihydroxy-19-Kauranoic Acid
Catalog No.:BCC9227
CAS No.:74365-74-5
- 4-hydroxyephedrine hydrochloride
Catalog No.:BCC8103
CAS No.:7437-54-9
- 8-Geranyloxypsoralen
Catalog No.:BCN4296
CAS No.:7437-55-0
- Leuprolide Acetate
Catalog No.:BCC1701
CAS No.:74381-53-6
- PAF (C16)
Catalog No.:BCC7522
CAS No.:74389-68-7
- Symlandine
Catalog No.:BCN1974
CAS No.:74410-74-5
Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds.[Pubmed:28512639]
Biomed Res Int. 2017;2017:7375615.
Blocking the polyol pathway plays an important role preventing diabetic complications. Therefore, aldose reductase (AR) and advanced glycation endproducts (AGEs) formation has significant effect on diabetic complications. Artemisia iwayomogi has long been used as treatment of various diseases in Korea. However, no literatures have reported on AR and AGEs formation inhibitory activities of A. iwayomogi. For these reasons, we aimed to assess that A. iwayomogi had potential as anti-diabetic complications agents. We led to isolation of two coumarins (1 and 2), nine flavonoids (3-11), five caffeoylquinic acids (12-16), three diterpene glycosides (17-19), and one phenolic compound (20) from A. iwayomogi. Among them, hispidulin (4), 6-methoxytricin (6), arteanoflavone (7), Quercetin-3-gentiobioside (10), 1,3-di-O-caffeoylquinic acid (13), and suavioside A (18) were first reported on the isolation from A. iwayomogi. Not only two coumarins (1 and 2), nine flavonoids (3-11), and five caffeoylquinic acids (12-16) but also extracts showed significant inhibitor on AR and AGEs formation activities. We analyzed contents of major bioactive compounds in Korea's various regions of A. iwayomogi. Overall, we selected Yangyang, Gangwon-do, from June, which contained the highest amounts of bioactive compounds, as suitable areas for cultivating A. iwayomogi as preventive or therapeutic agent in the treatment of diabetic complications.