Biorobin

CAS# 17297-56-2

Biorobin

Catalog No. BCN4691----Order now to get a substantial discount!

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Biorobin: 5mg $322 In Stock
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Quality Control of Biorobin

Number of papers citing our products

Chemical structure

Biorobin

3D structure

Chemical Properties of Biorobin

Cas No. 17297-56-2 SDF Download SDF
PubChem ID 15944778 Appearance Yellow powder
Formula C27H30O15 M.Wt 594.53
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
SMILES CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)O)O)O)O)O)O
Standard InChIKey RTATXGUCZHCSNG-KYGWAIEOSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Biorobin

The herbs of Cassia occidentalis

Biological Activity of Biorobin

DescriptionStandard reference
In vitro

Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.[Pubmed: 18214815]

Planta Med. 2008 Feb;74(2):171-4.


METHODS AND RESULTS:
The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, Biorobin and robinin were isolated from the aerial parts of Consolida oliveriana.
CONCLUSIONS:
Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.

Protocol of Biorobin

Structure Identification
Fitoterapia. 2006 Sep;77(6):484-6.

Flavonoids from Acalypha indica.[Pubmed: 16828241]


METHODS AND RESULTS:
Four known kaempferol glycosides, mauritianin, clitorin, nicotiflorin and Biorobin, have been isolated from the flowers and leaves of Acalypha indica. Some formerly published NMR data were corrected.

Biorobin Dilution Calculator

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Biorobin Molarity Calculator

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Preparing Stock Solutions of Biorobin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.682 mL 8.41 mL 16.82 mL 33.64 mL 42.05 mL
5 mM 0.3364 mL 1.682 mL 3.364 mL 6.728 mL 8.41 mL
10 mM 0.1682 mL 0.841 mL 1.682 mL 3.364 mL 4.205 mL
50 mM 0.0336 mL 0.1682 mL 0.3364 mL 0.6728 mL 0.841 mL
100 mM 0.0168 mL 0.0841 mL 0.1682 mL 0.3364 mL 0.4205 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Biorobin

Flavonoids from Acalypha indica.[Pubmed:16828241]

Fitoterapia. 2006 Sep;77(6):484-6.

Four known kaempferol glycosides, mauritianin, clitorin, nicotiflorin and Biorobin, have been isolated from the flowers and leaves of Acalypha indica. Some formerly published NMR data were corrected.

Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.[Pubmed:18214815]

Planta Med. 2008 Feb;74(2):171-4.

The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, Biorobin and robinin were isolated from the aerial parts of Consolida oliveriana. Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.

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