Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5463 | Lipiferolide |
| 1. Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against several tumor cells. 2. Liriodenine has antiplasmodial activity. 3. Lipiferolide and epitulipinolide diepoxide possess cytotoxic activity against KB cells. | |
| BCN5483 | Pinostilbene |
| 1. Pinostilbene has protective effects against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells, it can reduce release of lactate dehydrogenase and activity of caspase-3 triggered by 6-hydroxydopamine (6-OHDA) in a dose-dependent manner. 2. Pinostilbene can significantly inhibit the growth of human colon cancer cells, i.e., HCT116 and HT29, 20 and 40 uM of pinostilbene causes cell cycle arrest at S phase and induces apoptosis in colon cancer cells. | |
| BCN5484 | Catechin 7-xyloside |
| 1. Catechin-7-O-xyloside induces apoptosis via endoplasmic reticulum stress and mitochondrial dysfunction in human non-small cell lung carcinoma H1299 cells, suggests that it has anti-cancer activity. | |
| BCN5485 | Santamarine |
| 1. Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. 2. Santamarine and reynosin show bactericidal activity against clinical strains of Mycobacterium tuberculosis. | |
| BCN5487 | Crategolic acid |
| Crategolic acid(Maslinic acid) has neuroprotective, anti-inflammatory, anti- osteoporosis, cytotoxic and antiviral activities, it suppresses RANKL-induced osteoclastogenesis through NF-κB and MAPK/AP-1 signaling pathways , and has beneficial effects on hypoxic neurons by suppressing iNOS activation.Crategolic acid as a feed additive to stimulate growth and hepatic protein-turnover rates in rainbow trout ( Onchorhynchus mykiss ). | |
