Products with Anticholinesterase bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1214 | 3-Isomangostin |
| 3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial activity with IC50 values in the range of 4.71-11.40 uM. | |
| BCN1273 | Dictamnine |
| Dictamnine shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells, it at higher concentrations(≥100uM) has potential hepatotoxicity because of the cell membrane damage and mitochondrial membrane damage. | |
| BCN1486 | Leptomerine |
| 1. Leptomerine (IC₅₀ = 2.5 mM) shows potent anticholinesterasic activity. | |
| BCN1601 | 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone |
| 1. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone inhibits cholinesterase enzyme in a dose-dependent manner against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. 2. 5′-Geranyl-5,7,2′,4′-tetrahydroxyflavone shows better tyrosinase inhibitory activities than kojic acid. | |
| BCN1646 | 1,4,7-Eudesmanetriol |
| 1. 1α,4β,7β-Eudesmanetriol and 1β,4β,7β-Eudesmanetriol can inhibit growth of Pseudomonas stutzeri with a MIC value of 117 uM, they also show remarkable activities against acetylcholinesterase enzyme with IC50 values ranging between 25 and 26 uM. | |
