Products with
Anticholinesterase bioactivity
Cat.No.
|
Product Name
|
BCN2974 |
Dehydroevodiamine
|
Dehydroevodiamine has anticholinesterase activity and an anti-amnesic effect, it also may be a novel and effective ligand for improvement of beta-amyloid type amnesia. Dehydroevodiamine has antiarrhythmic, and anti-inflammatory properties, the effect of dehydroevodiamine-mediated inhibition of the expression LPS-induced iNOS and COX-2 genes is due to under the suppression of NF-kappaB activation in the transcriptional level. |
BCN3143 |
1,2-Didehydrotanshinone IIA
|
1. 1,2-Didehydrotanshinone IIA shows inhibitory effects against acetyl- (AChE) and butyrylcholinesterase (BChE).
2. 1,2-Didehydrotanshinone IIA possesses metal-chelation capacity. |
BCN3174 |
Mahanimbine
|
1. Mahanimbine inhibits AChE activity in a dose-dependent manner.
2. Mahanimbine and mangiferin increases the glucose utilization in a dose-dependent manner, can prevent obesity and use in management of diabetes.
3. Mahanimbine can prevent high-fat diet (HFD)-induced hyperlipidemia and fat accumulation in adipose tissue and liver along with the restricted progression of systemic inflammation and oxidative stress.
4. Mahanimbine can lower the absorption of dietary fat resulting in dietary fat excretion. |
BCN3357 |
1,3,5-Trihydroxyxanthone
|
1. 1,3,5-Trihydroxyxanthone has selective inhibitory activity on platelet aggregation induced by adenosine diphosphate. |
BCN3382 |
Gnetol
|
1. Gnetol has a strong inhibitory effect on murine tyrosinase activity.
2. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells.
3. Gnetol has the IC(50) value of 1.3 uM towards butyrylcholinesterase and shows a reversible and competitive inhibition in the kinetic study.
4. Gnetol is active in the inhibition of arachidonic acid (AA)-induced platelet aggregation. |