Products with Anticholinesterase bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6212 | Dunnianol |
| Dunnianol, macranthol and isodunnianol have anti-inflammatory activity, they can increase NAG-1(multiple targets related to inflammation) activity 1.5-3.0 fold and decrease cellular oxidative stress by 40-65%, they show substantial activity against iNOS. | |
| BCN6471 | Macusine B |
| 1. Macusine B is a dual inhibitor, has almost equal inhibitory activity on both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). | |
| BCN6651 | Dehydroevodiamine Chloride |
| Dehydroevodiamine hydrochloride has novel anti-cholinesterase and antiamnesic activities, it inhibits acetylcholinesterase activity in a dose-dependent and non-competitive manner(IC50=37.8 microM); its potent antiamnesic effect is thought to be due to the combined effects of acetylcholinesterase inhibition and the known cerebral blood flow enhancement. Dehydroevodiamine hydrochloride (0.1-0.3 mg/kg iv) can increase the cerebral blood flow recorded from the surface of the supra-sylvian gyrus in anesthetized cats, suggest that it selectively increases cerebral blood flow. | |
| BCN6789 | Alloisoimperatorin |
| Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoimperatorin has estrogenic activity on the Ishikawa cell line, it shows strong ability to induce alkaline phosphatase (AP) with the EC50 values of 0.8 microg/mL. | |
| BCN6798 | Corynoxidine |
| 1. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains. 2. Corynoxidine inhibits acetylcholinesterase activity in a dose-dependent manner, and the IC50 value of 89.0 microM. | |
