Products with Anticholinesterase bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3444 | Kobophenol A |
| Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-dependent manner, and the IC50 value is 115.8mM. Kobophenol A has protective effect against nitrosative/oxidative or mitochondrial damages resulted in the inhibition of the ROS, intracellular calcium ion level, and mitochondrial transmembrane potential changes on SH-SY5Y cells. | |
| BCN3468 | Skimmianin |
| 1. Skimmianine is a new inhibitor against the Leishmania APRT enzyme. 2. Skimmianine has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats. 3, Skimmianine is a strong acetylcholinesterase (AChE) inhibitor. 4. Skimmianine has anti-inflammatory properties. 5. Skimmianine has leishmanicidal effect , it is thus a promising drug candidate for L. braziliensis due to its potent immunomodulatory activity. | |
| BCN3525 | Curcumadione |
| 1. Curcumadione shows certain acetylcholinesterase inhibitory activity. | |
| BCN3961 | 8-Lavandulylkaempferol |
| 1. 8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, respectively. 2. 8-Lavandulylkaempferol shows inhibitory activities against aldose reductase, with the the IC50 of 0.79 microM. | |
| BCN4140 | Vasicine |
| 1. Vasicine is oxytocic and abortifacient agents. 2. Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. 3. Vasicine can regulate the inflammatory reaction, have great potentials to develop safe medications for respiratory and reproductive medicine. | |
