DunnianolCAS# 139726-29-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 139726-29-7 | SDF | Download SDF |
PubChem ID | 15714605 | Appearance | Powder |
Formula | C27H26O3 | M.Wt | 398.5 |
Type of Compound | Lignans | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 2,6-bis(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphenol | ||
SMILES | C=CCC1=CC(=C(C=C1)O)C2=CC(=CC(=C2O)C3=C(C=CC(=C3)CC=C)O)CC=C | ||
Standard InChIKey | PLBCEMUNKQWXGZ-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C27H26O3/c1-4-7-18-10-12-25(28)21(14-18)23-16-20(9-6-3)17-24(27(23)30)22-15-19(8-5-2)11-13-26(22)29/h4-6,10-17,28-30H,1-3,7-9H2 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Dunnianol, macranthol and isodunnianol have anti-inflammatory activity, they can increase NAG-1(multiple targets related to inflammation) activity 1.5-3.0 fold and decrease cellular oxidative stress by 40-65%, they show substantial activity against iNOS. |
Targets | NF-kB | NOS | ROS |
In vitro | Compounds from the bark of Illicium tsaii and their anti-inflammatory activity[Reference: WebLink]Planta Med.,2014, 80(10):807-807.Illicium tsaii is a Chinese native species growing in northwest China. The bark of I. tsaii, has been applied for the treatment of rheumatoid arthritis.
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Structure Identification | Synlett (Impact Factor: 2.46). 03/2010; 2010(04):633-635.A Concise Synthesis of Dunnianol[Reference: WebLink]
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Dunnianol Dilution Calculator
Dunnianol Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.5094 mL | 12.5471 mL | 25.0941 mL | 50.1882 mL | 62.7353 mL |
5 mM | 0.5019 mL | 2.5094 mL | 5.0188 mL | 10.0376 mL | 12.5471 mL |
10 mM | 0.2509 mL | 1.2547 mL | 2.5094 mL | 5.0188 mL | 6.2735 mL |
50 mM | 0.0502 mL | 0.2509 mL | 0.5019 mL | 1.0038 mL | 1.2547 mL |
100 mM | 0.0251 mL | 0.1255 mL | 0.2509 mL | 0.5019 mL | 0.6274 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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A Concise Synthesis of Dunnianol
Synlett (Impact Factor: 2.46). 03/2010; 2010(04):633-635.
A short total synthesis of the neosesquilignan Dunnianol which features a double Suzuki cross-coupling as a key step is described.