Gardenine

CAS# 139682-36-3

Gardenine

Catalog No. BCN6211----Order now to get a substantial discount!

Product Name & Size Price Stock
Gardenine: 5mg $886 In Stock
Gardenine: 10mg Please Inquire In Stock
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Quality Control of Gardenine

Number of papers citing our products

Chemical structure

Gardenine

3D structure

Chemical Properties of Gardenine

Cas No. 139682-36-3 SDF Download SDF
PubChem ID 197414 Appearance Oil
Formula C11H13NO4 M.Wt 223.2
Type of Compound Iridoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES COC(=O)C1=CNC2C3C1C=CC3(CO2)O
Standard InChIKey QIGMCZARMNNIKC-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H13NO4/c1-15-10(13)7-4-12-9-8-6(7)2-3-11(8,14)5-16-9/h2-4,6,8-9,12,14H,5H2,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Gardenine

The herbs of Nauclea officinalis

Biological Activity of Gardenine

Description1. Gardenin has regulatory effect on the gene expression in rats with focal cerebral ischemia.

Gardenine Dilution Calculator

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Gardenine Molarity Calculator

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Preparing Stock Solutions of Gardenine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4803 mL 22.4014 mL 44.8029 mL 89.6057 mL 112.0072 mL
5 mM 0.8961 mL 4.4803 mL 8.9606 mL 17.9211 mL 22.4014 mL
10 mM 0.448 mL 2.2401 mL 4.4803 mL 8.9606 mL 11.2007 mL
50 mM 0.0896 mL 0.448 mL 0.8961 mL 1.7921 mL 2.2401 mL
100 mM 0.0448 mL 0.224 mL 0.448 mL 0.8961 mL 1.1201 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Gardenine

Formation of nitrogen-containing metabolites from geniposide and gardenoside by human intestinal bacteria.[Pubmed:1818345]

Planta Med. 1991 Dec;57(6):536-42.

During the course of our studies on the metabolism of iridoid glycosides by human intestinal bacteria, we found that geniposide (1) and gardenoside (4) were transformed to new nitrogen-containing compounds, genipinine (3) and Gardenine (6), respectively, along with the known aglycones. Although the amounts of new metabolites were somewhat lower than those of the aglycones, they were quantitatively analyzed by means of liquid chromatography/mass spectrometry (LC/MS). Of 25 strains of human intestinal bacteria, Peptostreptococcus anaerobius, Klebsiella pneumoniae, Fusobacterium nucleatum, and Bacteroides fragilis ssp. thetaotus produced appreciable amounts of 3, while a bacterial mixture of human feces produced 10 times or more higher amounts of 3, as compared to the individual strains.

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