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2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

CAS# 139525-77-2

2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

2D Structure

Catalog No. BCN1574----Order now to get a substantial discount!

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2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride: 5mg $17 In Stock
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Quality Control of 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

3D structure

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2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

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Chemical Properties of 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

Cas No. 139525-77-2 SDF Download SDF
PubChem ID 16050055 Appearance Cryst.
Formula C13H16ClNO M.Wt 237.73
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-(7-methoxynaphthalen-1-yl)ethanamine;hydrochloride
SMILES COC1=CC2=C(C=CC=C2CCN)C=C1.Cl
Standard InChIKey HPYGZUDDGWEYDQ-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Protocol of 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

Structure Identification
SI20050030417T on 11 Feb 2005.

Novel process for synthesizing and a novel crystal form of agomelatin as well as pharmaceutical preparations containing these.[Reference: WebLink]


METHODS AND RESULTS:
Producing agomelatin comprises reacting 7-methoxy-1-tetralone with cyanoacetic acid in presence of organo-ammonium carboxylate catalyst (V), contacting resulting 2-(7-methoxy-3,4-dihydro-1-naphthyl)acetonitrile (VI) with hydrogenation catalyst in presence of allylic compound to give 2-(7-methoxy-1-naphthyl)acetonitrile (VII), hydrogenating (VII) to give 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride (VIII) and acetylating. Producing agomelatin (N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide) comprises: (i) reacting 7-methoxy-1-tetralone with cyanoacetic acid in the presence of an organoammonium carboxylate catalyst of formula (V) while removing water; (ii) contacting the resulting 2-(7-methoxy-3,4-dihydro-1-naphthyl)acetonitrile (VI) with a hydrogenation catalyst in the presence of an allylic compound to give 2-(7-methoxy-1-naphthyl)acetonitrile (VII); (iii) hydrogenating (VII) in the presence of Raney nickel in ethanol and treating the product with hydrochloric acid to give 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride (VIII); and (iv) reacting (VIII) successively with.

2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride Dilution Calculator

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2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride Molarity Calculator

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Preparing Stock Solutions of 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2065 mL 21.0323 mL 42.0645 mL 84.1291 mL 105.1613 mL
5 mM 0.8413 mL 4.2065 mL 8.4129 mL 16.8258 mL 21.0323 mL
10 mM 0.4206 mL 2.1032 mL 4.2065 mL 8.4129 mL 10.5161 mL
50 mM 0.0841 mL 0.4206 mL 0.8413 mL 1.6826 mL 2.1032 mL
100 mM 0.0421 mL 0.2103 mL 0.4206 mL 0.8413 mL 1.0516 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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