Tenuifoliside BCAS# 139726-36-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 139726-36-6 | SDF | Download SDF |
| PubChem ID | 10055215 | Appearance | Powder |
| Formula | C30H36O17 | M.Wt | 668.6 |
| Type of Compound | Phenylpropanoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2S,3S,4R,5R)-4-hydroxy-3-[(E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]oxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxyoxan-2-yl]methyl 4-hydroxybenzoate | ||
| SMILES | COC1=CC(=CC(=C1O)OC)C=CC(=O)OC2C(C(OC2(CO)OC3C(C(C(C(O3)COC(=O)C4=CC=C(C=C4)O)O)O)O)CO)O | ||
| Standard InChIKey | HBYKIOIUVMDUIK-GUJRDUPISA-N | ||
| Standard InChI | InChI=1S/C30H36O17/c1-41-17-9-14(10-18(42-2)22(17)35)3-8-21(34)45-27-24(37)19(11-31)46-30(27,13-32)47-29-26(39)25(38)23(36)20(44-29)12-43-28(40)15-4-6-16(33)7-5-15/h3-10,19-20,23-27,29,31-33,35-39H,11-13H2,1-2H3/b8-3+/t19-,20-,23-,24-,25+,26-,27+,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Polygala tenuifolia
| Description | 1. Tenuifoliside B is a target lactate dehydrogenase inhibitor. 2. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment in mice. |
| Targets | AChR |
Tenuifoliside B Dilution Calculator
Tenuifoliside B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.4957 mL | 7.4783 mL | 14.9566 mL | 29.9133 mL | 37.3916 mL |
| 5 mM | 0.2991 mL | 1.4957 mL | 2.9913 mL | 5.9827 mL | 7.4783 mL |
| 10 mM | 0.1496 mL | 0.7478 mL | 1.4957 mL | 2.9913 mL | 3.7392 mL |
| 50 mM | 0.0299 mL | 0.1496 mL | 0.2991 mL | 0.5983 mL | 0.7478 mL |
| 100 mM | 0.015 mL | 0.0748 mL | 0.1496 mL | 0.2991 mL | 0.3739 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Tenuifoliside A
Catalog No.:BCN2893
CAS No.:139726-35-5
- Isodunnianol
Catalog No.:BCN6213
CAS No.:139726-30-0
- Dunnianol
Catalog No.:BCN6212
CAS No.:139726-29-7
- BS-181 HCl
Catalog No.:BCC2537
CAS No.:1397219-81-6
- Yunnanxane
Catalog No.:BCN6702
CAS No.:139713-81-8
- Amphotericin B
Catalog No.:BCN2564
CAS No.:1397-89-3
- Gardenine
Catalog No.:BCN6211
CAS No.:139682-36-3
- EPZ005687
Catalog No.:BCC2219
CAS No.:1396772-26-1
- CGP 52432
Catalog No.:BCC6989
CAS No.:139667-74-6
- PR 39 (porcine)
Catalog No.:BCC5856
CAS No.:139637-11-9
- Purotoxin 1
Catalog No.:BCC6333
CAS No.:1396322-38-5
- 3-Bromoisonicotinic Acid
Catalog No.:BCC8368
CAS No.:13959-02-9
New Products
- tenuifoliside C
Catalog No.:BCN8299
CAS No.:139726-37-7
- Sildenafil
Catalog No.:BCC1947
CAS No.:139755-83-2
- Cucurbitacin E-2-O-Glucoside
Catalog No.:BCC8156
CAS No.:1398-78-3
- Milameline hydrochloride
Catalog No.:BCC7427
CAS No.:139886-04-7
- 3,6'-Disinapoyl sucrose
Catalog No.:BCN2719
CAS No.:139891-98-8
- Globularin
Catalog No.:BCN6215
CAS No.:1399-49-1
- Drahebenine
Catalog No.:BCN7044
CAS No.:1399049-43-4
- Alpinone 3-acetate
Catalog No.:BCN7768
CAS No.:139906-49-3
- Palbinone
Catalog No.:BCN3930
CAS No.:139954-00-0
- Cinnamic acid
Catalog No.:BCN6217
CAS No.:140-10-3
- Nithiamide
Catalog No.:BCC4687
CAS No.:140-40-9
- Pentamidine isethionate
Catalog No.:BCC5644
CAS No.:140-64-7
Cognitive improving and cerebral protective effects of acylated oligosaccharides in Polygala tenuifolia.[Pubmed:15256744]
Biol Pharm Bull. 2004 Jul;27(7):1081-5.
We studied the cognitive improving and cerebral protective constituents in the roots of Polygala tenuifolia Willdenow, a well-known Chinese traditional medicine prescribed for amnesia, neurasthenia, palpitation, noctural emission and insomnia. Tenuifoliside B (1), which is one of the acylated oligosaccharides in the roots of P. tenuifolia, showed the cerebral protective effect on potassium cyanide (KCN)-induced anoxia in mice, widely used as an animal model for cerebrovascular disease, and also had an ameliorative effect on the scopolamine-induced impairment of performance in passive avoidance task in rats. Compound 1 significantly enhanced oxotremorine-induced tremors in mice, suggesting that it ameliorated the scopolamine-induced impairment of passive avoidance response by enhancing the cholinergic system. These findings show that compound 1 has cognitive improving and cerebral protective effects.
Tenuifoliside B, a component isolated from Polygalae Radix, inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. Tenuifoliside B shows potential cognitive improvement and cerebral protective effects. Tenuifoliside B has potential to become an anti-AD lead compound.
Tenuifoliside B,139726-36-6,Natural Products, buy Tenuifoliside B , Tenuifoliside B supplier , purchase Tenuifoliside B , Tenuifoliside B cost , Tenuifoliside B manufacturer , order Tenuifoliside B , high purity Tenuifoliside B
