Products with Estrogenic effect bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2285 | Sagittatoside A |
| Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα, and sagittatoside A and icariin induces ERα phosphorylation at serine 118 residue. | |
| BCN2339 | Gypenoside XVII |
| Gypenoside XVII confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, inactivation of GSK-3β and activation of Nrf2/ARE/HO-1 pathways. Gypenoside XVII has protective effects to the cellular and rodent models of Alzheimer's disease by activating TFEB. | |
| BCN2623 | Cimicifugoside |
| 1. Cimicifugoside is a novel specific nucleoside transport inhibitor that displays synergistic potentiation of methotrexate cytotoxicity. 2. Cimicifugoside is a phytoestrogen, it can selectively inhibit nicotinic acetylcholine receptor (nAChR) -mediated response in bovine chromaffin cells. 3. Cimicifugoside shows immunosuppressive activity, which is preferentially directed toward B-cell function with larger doses being required for suppression of T-cell function. | |
| BCN2707 | 7-Methoxycoumarin |
| 7-Methoxycoumarin, also known as Herniarin, has potent antioxidant, hepatoprotective, and antitumor effects. 7-Methoxycoumarin has a weak estrogenic activity in vitro and in vivo, it could be beneficial with regard to vagina dryness as it showed a tissue specific effect without exposing the uterus to a potential tumorigenic growth. | |
| BCN2855 | 4',7-Isoflavandiol |
| 4',7-Isoflavandiol, an estrogen metabolite, affects the ability of soy nuts to improve cardiovascular risk factors. 4',7-Isoflavandiol is a potential anticancer agent against HeLa, with possible mechanisms involved in ROS generation and mitochondrial membrane alteration; it may advance breast cancer potential via up-regulation of the eukaryotic initiation factor 4GI (eIF4GI). | |
