Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1929 | Cochlearine |
| 1. Cochlearines A can significantly inhibit Cav3.1 T-type calcium channel (TTCC) and show noticeable selectivity against Cav1.2, Cav2.1, Cav2.2, and Kv11.1 (hERG) channels; and TTCC inhibitors hold great potential for the treatment of a variety of neurological disorders. | |
| BCN1934 | Tropacocaine |
| 1. Tropacocaine inhibits norepinephrine uptake at the concentration of 30 microM. 2. Tropacocaine can inhibit the spontaneous and veratridine-induced release of newly synthesized acetylcholine, but not via activation of presynaptic muscarinic receptors. 3. Tropacocaine can attenuate the oxotremorine-induced inhibition of the release of acetylcholine, suggesting antimuscarinic activity. 4. Tropacocaine has cardiovascular effects. | |
| BCN1942 | Scopoline |
| 1. Scopoline, tropinol, ecgonine, and granatoline derivatives are therapeutic agents of the pyrrole and pyridine group. 2. Scopoletin and scopolin can contribute to a cooperative effect causing plant inhibition in the natural environment and therefore be a factor of ecological significance. 3. Scopoline has fungitoxic effects, it is inhibitory to Sclerotinia at similar doses to scopoletin; as scopolin is known to be less phytotoxic than ayapin and scopoletin, its accumulation may well confer head rot resistance with minimal plant damage and might be one of the bases for resistance to Sclerotinia. | |
| BCN1958 | Bohemamine |
| 1. Bohemamine is a cell adhesion inhibitor, it inhibits adhesion of HL-60 cells to CHO-ICAM-1 cells at IC50 values of 27.2 microg/ml . | |
| BCN1982 | Heliotrine |
| 1. The pyrrolizidine alkaloid Heliotrine interferes with reporter signals derived from GAL4-based nuclear receptor transactivation assays by a mechanism independent of luciferase enzyme inhibition. 2. Acute hepatitis induced by Heliotrine is accompanied by uncoupling of oxidative phosphorylation in liver mitochondria. | |
