Products with Inhibitors Bioactivity

Explore BioCrick products associated with Inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN2295	Desmethoxy yangonin
Desmethoxyyangonin is a reversible inhibitor of MAO-B, it may have important therapeutic value for treatment of neurodegenerative disorders and Parkinson's Disease. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.
BCN2297	Bufarenogin
1. ψ-Bufarenogin exhibits potent therapeutic effect in xenografted human hepatoma without notable side effects,at least partially,via inhibiting receptor tyrosine kinases-regulated signaling. 2. ψ-Bufarenogin has inhibitory activity on human kidney Na(+)/K(+)-ATPase. 3. ψ-Bufarenogin has cytotoxicity against HepG2 and MCF-7 human cancer cells.
BCN2298	11-Keto-beta-boswellic acid
11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenase; and it can increase the Nrf2 and HO-1 expression, which provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. 11-Keto-beta-boswellic acid possesses significant anti-inflammatory, and anti-tumoral activities.
BCN2306	Methysticin
1. Methysticin and yangonin show in vitro hepatotoxicity on human hepatocytes (HepG2) . 2. Methysticin and 7,8-dihydroMethysticin contribute to CYP1A1 induction. 3. Methysticin is a potent NF-kappaB inhibitor in kava with minimum toxicity. 4. Methysticin possesses anticonvulsant and neuroprotective properties, possibly by interfering with frequency potentiation.
BCN2308	Dihydroisotanshinone I
Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scavenging activity and inhibition of lipid peroxidation.

Inhibitors Bioactivity Products