Products with Inhibitors Bioactivity

Explore BioCrick products associated with Inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN4477	Umbelliferone
Umbelliferone is a competitive inhibitor of alkaline phosphatase. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with antinociceptive, anti-inflammatory, anti-hyperglycaemic, anti-allergic, molluscicidal and anti-tumor activities. Umbelliferone has stimulatory effect on adipocyte differentiation likely occurs through up-regulation of adipogenic transcription factors and downstream adipocyte-specific gene expression.
BCN4494	Sappanchalcone
1. Sappanchalcone has cytoprotective effect. 2. Sappanchalcone blocks cell cycle progression in the G2/M phase, brazilin inhibited TNFα/NF-κB signaling. 3. Sappanchalcone has anti-inflammatory effect, could be used as an anti-inflammatory and bone-protective agent during the treatment of rheumatoid arthritis. 4. Sappanchalcone suppresses oral cancer cell growth and induces apoptosis through the activation of p53-dependent mitochondrial, p38, ERK, JNK, and NF-κB signaling, could potentially used to treat periodontal, pulpal , periapical inflammatory lesion and oral cancer. 5. Sappanchalcone possesses the most potent effect against allergic reaction in basophilic leukemic (RBL-2H3) cells with an inhibitory concentration (IC50) value of 7.6 uM, it may have anti-allergic activity. 6. Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.
BCN4497	Isomartynoside
1. Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. 2. Isomartynoside shows obvious anti-fatigue activity.
BCN4521	Aristolactam AIIIa
1. Aristolactam AIIIa has anti-tumor activity. 2. Aristolactam AIIIa was identified as a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD). 3. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid.
BCN4525	Cycloart-22-ene-3,25-diol
1. Cycloart-22-ene-3,25-diol shows tyrosinase inhibitory activity, the IC50 value of 77.5 uM .

Inhibitors Bioactivity Products