Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4788 | Warangalone |
| 1. Warangalone shows significant cytotoxicity against HL-60 cells. 2. Warangalone with cAK may contribute to its biological effects in vivo and to the insecticidal activity of the plant D. scandens. 3. Warangalone is a powerful inhibitor of protein kinase A, shows marked effectiveness as an anti-inflammatory on the phospholipase A(2)-induced paw edema and on the 12-O-tetradecanoylphorbol 13-acetate-induced ear edema in mice, after systemic and local administration, respectively. | |
| BCN4791 | Neorauflavane |
| 1. Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM. 2. Neorauflavane can efficiently reduce melanin content in B16 melanoma cells with 12.95 uM of IC50. | |
| BCN4795 | 4-Hydroxyphenylacetic acid |
| 4-Hydroxyphenylacetic acid has anti-inflammatory activity,it attenuates inflammation and edema through suppressing hypertonic and hypoxic induction of HIF-1α in seawater aspiration-induced lung injury in rats. 4-Hydroxyphenylacetic acid is active against the root-lesion nematode, Pratylenchus penetrans, and the pine wood nematode. | |
| BCN4796 | 14-Deoxycoleon U |
| 1. 14-Deoxycoleon U has anti-termitic activity. 2. 14-Deoxycoleon U is highly active against both wood-decay fungi. 3. 14-Deoxycoleon U shows antibacterial activity against the Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Micrococcus luteus. | |
| BCN4801 | Dalbergioidin |
| 1. Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. 2. Dalbergioidin shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. 3. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. 4. Dalbergioidin ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. | |
